Document Detail


Evaluation of the patient with recurrent bacterial infections.
MedLine Citation:
PMID:  9509258     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Recurrent bacterial infection is a complaint encountered regularly in the course of both adult and pediatric care. Defects of neutrophils and monocytes are most commonly associated with recurrent infection, but abnormalities of immunoglobulins and complement must be considered. Defensins, small antibacterial peptides, have been implicated recently in some of the infectious diathesis of cystic fibrosis. A thorough history and physical examination focused on severity, sequelae, and microbiology of infections can usually determine whether a patient needs further evaluation. The diseases and syndromes most frequently associated with recurrent infection are presented, along with discriminating clinical, pathologic, and microbiologic features.
Authors:
S M Holland; J I Gallin
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Annual review of medicine     Volume:  49     ISSN:  0066-4219     ISO Abbreviation:  Annu. Rev. Med.     Publication Date:  1998  
Date Detail:
Created Date:  1998-04-30     Completed Date:  1998-04-30     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  2985151R     Medline TA:  Annu Rev Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  185-99     Citation Subset:  IM    
Affiliation:
Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. smh@nih.gov
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Infective Agents / pharmacology
Bacterial Infections / complications,  diagnosis*,  immunology,  microbiology,  physiopathology
Blood Bactericidal Activity / physiology
Blood Proteins / physiology
Child
Complement System Proteins / immunology
Cystic Fibrosis / blood,  diagnosis
Defensins
Disease
Humans
Immunoglobulins / immunology
Medical History Taking
Monocytes / physiology
Neutrophils / physiology
Physical Examination
Recurrence
Severity of Illness Index
Syndrome
Chemical
Reg. No./Substance:
0/Anti-Infective Agents; 0/Blood Proteins; 0/Defensins; 0/Immunoglobulins; 9007-36-7/Complement System Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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