| Evaluation of oxidative and nitrosative stress in hemodialysis patients. | |
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MedLine Citation:
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PMID: 21048552 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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AIM: Oxidative/nitrosative stress has long been demonstrated in hemodialysis patients. It is associated with numerous complications such as atherosclerosis and related cardiovascular disturbances. However, the factors influencing oxidative/nitrosative status have not been characterized extensively in these patients. Therefore, the present study was designed to investigate the alteration of oxidative/nitrosative stress parameters and total antioxidant status. METHODS: Forty-one hemodialysis patients and 41 healthy subjects were enrolled in the present study. Serum myeloperoxidase, nitrotyrosine and total antioxidant capacity were determined. RESULTS: Serum myeloperoxidase and nitrotyrosine were significantly higher in the haemodialysis patients compared to the healthy subjects (P<0.05) while total antioxidant capacity was lower (P<0.01). CONCLUSION: According to the results of this study, oxidative and nitrosative stress is increased in haemodialysis patients, therefore these alterations should be considered in the treatment of these patients. |
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Authors:
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E S Namiduru; M Tarakcioglu; O Tiryaki; C Usalan |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Minerva medica Volume: 101 ISSN: 0026-4806 ISO Abbreviation: Minerva Med. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-11-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0400732 Medline TA: Minerva Med Country: Italy |
Other Details:
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Languages: eng Pagination: 305-10 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, Faculty of Medicine, University of Gaziantep Gaziantep, Turkey - enamiduru@gmail.com. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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