| Evaluation of a novel commercial rapid test for dengue diagnosis based on specific IgA detection. | |
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MedLine Citation:
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PMID: 22248735 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The performance of the novel commercial test ASSURE® Dengue IgA Rapid test (MP Diagnostics) was evaluated using a panel of 172 sera collected from dengue patients and 47 sera from healthy blood donors. The overall specificity and sensitivity were 61.0% and 85.1%, respectively. However, the positivity rate for IgA went from 33.3% for sera collected the same day of fever onset to 81.2% for sera collected 5 days after fever onset. Infections with serotype 2 viruses were detected more efficiently than those with serotype 1 viruses, and no sera from infections with serotypes 3 and 4 were available. In addition, the kit was twice more efficient at detecting secondary infections than at detecting primary infections. Finally, the ASSURE® test showed good repeatability and reproducibility. The results of this study suggest that the ASSURE® Dengue IgA Rapid test may become a useful and easy-to-use test for early dengue diagnosis. |
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Authors:
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Sergio Isaac de la Cruz Hernández; Silvia González Mateos; Hilario Flores Aguilar; Irma López Martinez; Celia Alpuche Aranda; Juan E Ludert; Rosa María Del Angel |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Diagnostic microbiology and infectious disease Volume: 72 ISSN: 1879-0070 ISO Abbreviation: Diagn. Microbiol. Infect. Dis. Publication Date: 2012 Feb |
Date Detail:
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Created Date: 2012-01-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8305899 Medline TA: Diagn Microbiol Infect Dis Country: United States |
Other Details:
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Languages: eng Pagination: 150-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Departamento de Virología, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Mexico D.F., Mexico; Departamento de Infectómica y Patogénesis Molecular, Centro de Investigación y Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Mexico D.F., Mexico. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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