Document Detail

Evaluation of normal neurological development of human fetuses from 21 to 30 weeks' gestation through fetal auditory evoked response.
MedLine Citation:
PMID:  19196213     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To evaluate the neurological maturation of fetuses between 21 and 30 weeks' gestation by the auditory evoked response. METHODS: The auditory evoked responses of 25 normal singleton fetuses were observed once a week from 21 to 30 weeks' gestation. The stimulus consisted of five pulses of sinusoidal waves, for 2 s, at 1500 cycles/s, with a sound pressure of 125 dB. RESULTS: Fetal auditory evoked response increased with neurological maturation, presenting two main points of positive discontinuity. The two points in the heart response were detected between the 24(th)/25(th) and the 27(th)/28(th) week. From the 27(th) week on, fetal motor response (FMR) was always present. Initial fetal heart response presented a fluctuation pattern between the 21(st) and the 30(th) week, with a tendency to increase as gestational age advanced. Fetal heart response also increased with gestational age. Late response (LR) fluctuated until the 29(th) week, and was always present after that period. CONCLUSIONS: The maturation of the fetal nervous system is clearly demonstrated by changes in the auditory evoked responses in different gestational ages, and presents some discontinuity points.
S??rgio Hecker Luz; Fabiano Candal Vasconcellos; Tatiana Kreling; Fernanda Silva Pacheco; M??rcia Lorena Fagundes Chaves
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  37     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2009  
Date Detail:
Created Date:  2009-10-23     Completed Date:  2010-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  270-5     Citation Subset:  IM    
Department of Gynecology and Obstetrics of Medical School Pontifical Catholic University of Rio Grande do Sul, Rio Grande do Sul, Brazil.
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MeSH Terms
Evoked Potentials, Auditory*
Fetal Development / physiology*
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Prospective Studies
Startle Reaction*

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