Document Detail

Evaluation of non-stimulated nitroblue-tetrazolium test in patients with malignant lymphomas.
MedLine Citation:
PMID:  728624     Owner:  NLM     Status:  MEDLINE    
The NBT-test was performed in 54 patients with Hodgkin and non-Hodgkin lymphoma showing no bacterial infection exept for one case. 18 patients presented, at onset of the disease, a number of neutrophilic NBT-reducing granulocytes at pathological levels (greater than 12%). In order to evaluate the influence of cytostatic drugs on NBT-test serial blood samples were taken during polychemotherapy in 17 patients with lymphoma. In our experience, cytostatics (COPP) do not necessarily lessen NBT-reducing activity of granulocytes. The results suggest that the NBT in malignant lymphomas could not be used as an indication of bacterial infection.
V Liso; G Specchia; G Troccoli
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Blut     Volume:  37     ISSN:  0006-5242     ISO Abbreviation:  Blut     Publication Date:  1978 Dec 
Date Detail:
Created Date:  1979-03-13     Completed Date:  1979-03-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173401     Medline TA:  Blut     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  313-7     Citation Subset:  IM    
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MeSH Terms
Bacterial Infections / complications,  diagnosis
Drug Therapy, Combination
Hodgkin Disease / complications,  diagnosis,  drug therapy
Lymphoma / complications,  diagnosis*,  drug therapy
Middle Aged
Nitroblue Tetrazolium / diagnostic use*
Tetrazolium Salts / diagnostic use*
Reg. No./Substance:
0/Tetrazolium Salts; 298-83-9/Nitroblue Tetrazolium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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