Document Detail

Evaluation of the new generation dual-lumen catheter for neonatal ECMO.
MedLine Citation:
PMID:  22918933     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The purpose of this study was to compare the newly designed dual-lumen venovenous catheter (VR13, OriGen Biomedical, Austin, TX) with the current dual-lumen catheter (VV12, OriGen Biomedical).
METHODS: Five newborn lambs, 1 to 5 days old and weighing 4.2 ± 0.5 kg, were cannulated with the VV13 OriGen catheter and placed on extracorporeal membrane oxygenation (ECMO). ECMO flows were increased from 200 to 600 ml/min, with measurements taken after the changes. The experiment was then repeated using the VV12 catheter.
RESULTS: Recirculation values were equal for both catheters. The pressure drop at the reinfusion port was equal for both catheters at 200 ml/min, increasing to 275 mmHg at 500 ml/min for the VR13 vs. 240 mmHg for the VV12 catheter.
CONCLUSION: These findings indicate that the VR13 catheter resulted in levels of recirculation equal to the VV12. Based on resistance measurements, we do not recommend the use of this new catheter beyond 400 ml/min until minor design changes are made.
M M Said; O Rivera; G T Mikesell; K Rais-Bahrami
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Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article     Date:  2012-08-22
Journal Detail:
Title:  Perfusion     Volume:  28     ISSN:  1477-111X     ISO Abbreviation:  Perfusion     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-24     Completed Date:  2013-06-07     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  8700166     Medline TA:  Perfusion     Country:  England    
Other Details:
Languages:  eng     Pagination:  26-30     Citation Subset:  IM    
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MeSH Terms
Animals, Newborn
Blood Pressure
Extracorporeal Membrane Oxygenation / instrumentation*,  methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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