Document Detail

Evaluation of new Japanese diagnostic criteria for disseminated intravascular coagulation in critically ill patients.
MedLine Citation:
PMID:  15678275     Owner:  NLM     Status:  MEDLINE    
New Japanese diagnostic criteria were prepared for disseminated intravascular coagulation (DIC) in critically ill patients and their usefulness was compared with the criteria of the International Society of Thrombosis and Haemostasis (ISTH) and those of the Japan Ministry of Health and Welfare (JMHW). In a retrospective study of patients with platelet counts of less than 150 x10(3)/mL, 52 cases (33.3%), 66 cases (42.3%), and 101 cases (64.7%) were diagnosed as DIC by the ISTH, JMHW, and new Japanese DIC criteria, respectively. The DIC state as diagnosed by the new Japanese DIC criteria included both DIC states as diagnosed by ISTH or JMHW criteria. Some DIC states diagnosed by the JMHW criteria included those diagnosed by ISHT criteria but this was not universal. The mortality of DIC as diagnosed by the ISTH or JMHW criteria was markedly high, compared to that for DIC diagnosed by the new Japanese criteria. The mortality of patients without DIC by ISTH was also high when they were diagnosed as DIC by the new Japanese criteria. The frequency of DIC by each set of diagnostic criteria was significantly higher in patients with infection than in those without infection. The mortality of DIC by each set of diagnostic criteria was significantly higher in patients with infection than in those without infection, and the mortality of overt-DIC by ISTH diagnostic criteria was also high in patients without infection.
Satoshi Gando; Hideo Wada; Hidesaku Asakura; Toshiaki Iba; Yutaka Eguchi; Kohji Okamoto; Yasuhiro Ohtomo; Kazuo Kawasugi; Shin Koga; Kazuhide Koseki; Hajime Tsuji; Toshihiko Mayumi; Atsuo Murata; Masao Nakagawa; Shigeatu Endo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis     Volume:  11     ISSN:  1076-0296     ISO Abbreviation:  Clin. Appl. Thromb. Hemost.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-01-28     Completed Date:  2005-06-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9508125     Medline TA:  Clin Appl Thromb Hemost     Country:  United States    
Other Details:
Languages:  eng     Pagination:  71-6     Citation Subset:  IM    
Department of Anesthesiology and Critical Care Medicine, Hokkaido University, Graduate School of Medicine, Sapporo-city, Japan.
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MeSH Terms
Critical Illness
Disseminated Intravascular Coagulation / classification*,  diagnosis*,  epidemiology,  mortality
Infection / epidemiology
Japan / epidemiology
Retrospective Studies

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