Document Detail


Evaluation of neonatal sepsis screening in a tropical area Part III: Neonatal sepsis in meconium stained deliveries.
MedLine Citation:
PMID:  11677909     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Of the 6,060 consecutive live births delivered at the University Maternity Unit of Guadeloupe (French West Indies) during a 30-month period, 635 newborns (10.4%) presented with meconium stained (MS) amniotic fluid, of which 595 (94%) received bacteriological screening at birth (light MS, n = 543; thick MS, n = 52). Thirty (5%) of MS newborns had a bacteraemia (n = 13, group B streptococcus, GBS), and 128 (21.5%) a bacterial positive gastric aspirate (n = 54, GBS). Sixty-six newborns among MS babies needed tracheal suctioning (11%) in the delivery room for meconium inhalation. Among these 595 screened MS newborns, 286 (48%) presented clinical signs of postmaturity at birth, having therefore an explanation for their MS condition. For the other MS newborns without the postmaturity explanation, we experienced twofold increased risk of neonatal sepsis (OR 1.88 for bacteraemia and 2.61 for external carriage p < 0.02, Chi square) as compared with their MS postmature counterparts. We conclude that when meconium stained deliveries are associated with postmaturity signs, one may not need to initiate prophylactic antibiotic treatment at birth unless they present with other traditional risk factors for neonatal sepsis such as intrapartum fever and prolonged rupture of membranes.
Authors:
P Y Robillard; T C Hulsey; J Périanin; J M Pérez; A Gallais; E Janky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The West Indian medical journal     Volume:  50     ISSN:  0043-3144     ISO Abbreviation:  West Indian Med J     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-10-25     Completed Date:  2001-12-04     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  0417410     Medline TA:  West Indian Med J     Country:  Jamaica    
Other Details:
Languages:  eng     Pagination:  130-2     Citation Subset:  IM    
Affiliation:
Centre Hospitalier Sud Réunion, BP 350, 97448 Saint-Pierre, La Réunioin, France.
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MeSH Terms
Descriptor/Qualifier:
Humans
Infant, Newborn
Meconium*
Neonatal Screening*
Risk Factors
Sepsis / diagnosis*,  epidemiology
West Indies / epidemiology

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