Document Detail

Evaluation of myocardial perfusion and left ventricular function six months after percutaneous transmyocardial laser revascularization: comparison of two Ho-YAG laser systems with the same wavelength, but different energy delivery and navigation systems.
MedLine Citation:
PMID:  14677154     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: Myocardial perfusion and left ventricular function (LVF) were assessed after percutaneous transmyocardial laser revascularization (PTMR) in patients not amenable to conventional revascularization, with a comparison of two laser systems. STUDY DESIGN/MATERIALS AND METHODS: PTMR was performed with an Eclipse laser in 15 patients, and with a Biosense DMR in 10 patients. (201)Thallium scintigraphy, coronary angiography, and ventriculography were performed at baseline and at the 7.5+/-4.3-month follow-up. All patients in the Biosense DMR group and 10 in the Eclipse group underwent NOGA mapping before PTMR and after follow-up. RESULTS: The event-free survival rates were comparable, and the angina scores of all patients improved significantly, but more so in the Biosense DMR group than in the Eclipse group (1.2+/-1.1 vs. 2.3+/-0.9, P < 0.05). Both, the electrical activity assessed by NOGA mapping and the normalized (201)thallium uptake at redistribution improved significantly in the treated segments after Biosense DMR, while the global LVF decreased insignificantly in the Eclipse group. CONCLUSIONS: PTMR resulted in significant improvements in the clinical symptoms, but the electrical activity improved only in the Biosense DMR group, without transforming to a better LVF.
Christoph Strehblow; Mariann Gyöngyösi; Aliasghar Khorsand; Wolfgang Sperker; Melanie Gatterer; Senta Graf; Heinz Sochor; Dietmar Glogar
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Lasers in surgery and medicine     Volume:  33     ISSN:  0196-8092     ISO Abbreviation:  Lasers Surg Med     Publication Date:  2003  
Date Detail:
Created Date:  2003-12-16     Completed Date:  2004-06-01     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8007168     Medline TA:  Lasers Surg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  273-81     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley-Liss, Inc.
Division of Cardiology, University of Vienna Medical Center, Vienna, Austria.
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MeSH Terms
Body Surface Potential Mapping
Coronary Artery Disease / therapy*
Coronary Circulation / radiation effects*
Exercise Tolerance
Follow-Up Studies
Heart / physiology
Laser Therapy / methods*
Middle Aged
Myocardial Reperfusion / methods
Myocardial Revascularization / methods*
Stereotaxic Techniques
Survival Analysis
Ventricular Function, Left / radiation effects*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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