Document Detail


Evaluation of mitral stenosis with velocity-encoded cine-magnetic resonance imaging.
MedLine Citation:
PMID:  7856529     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Velocity-encoded cine-magnetic resonance imaging (VEC-MRI) is a new method for quantitation of blood flow with the potential to measure high-velocity jets across stenotic valves. The objective of this study was to evaluate the ability of VEC-MRI to measure transmitral velocity in patients with mitral stenosis. Sixteen patients with known mitral stenosis were studied. A 1.5 Tesla superconducting magnet was used to obtain velocity-encoded images in the left ventricular short-axis plane. Images were obtained throughout the cardiac cycle at 3 consecutive slices beginning proximal to the mitral coaptation point. To determine the optimal slice thickness for MRI imaging, both 10 mm and 5 mm thicknesses were used. Echocardiography including continuous-wave Doppler was performed on every patient within 2 hours of MRI imaging. Peak velocity was determined for both VEC-MRI and Doppler-echo images. Two observers independently measured the VEC-MRI mitral inflow velocities. Of the 16 patients, imaged data were incomplete in only 1 study, and all images were adequate for analysis. Strong correlations were found for measurements of mitral valve gradient for both 10 mm (peak r = 0.89, mean r = 0.84) and 5 mm (peak r = 0.82, mean r = 0.95) slice thicknesses. Measurements of peak velocity with VEC-MRI (10 mm) agreed well with Doppler: mean 1.46 m/s, mean of differences (Doppler MRI) 0.38 m/s, standard deviation of differences 0.2 m/s. These findings suggest that VEC-MRI can noninvasively determine the severity of mitral stenosis.
Authors:
P A Heidenreich; J Steffens; N Fujita; M O'Sullivan; G R Caputo; E Foster; C B Higgins
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  75     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-03-14     Completed Date:  1995-03-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  365-9     Citation Subset:  AIM; IM    
Affiliation:
Department of Radiology, University of California, San Francisco 94142-0628.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Atrial Fibrillation / complications
Blood Flow Velocity
Echocardiography, Doppler
Female
Humans
Magnetic Resonance Imaging / methods*
Male
Middle Aged
Mitral Valve Stenosis / complications,  diagnosis*,  physiopathology*,  ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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