Document Detail

Evaluation of mifepristone as a once a month contraceptive pill.
MedLine Citation:
PMID:  19026402     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to assess the efficacy and safety of mifepristone as a contraceptive pill. STUDY DESIGN: A prospective case-control study was conducted in a tertiary care center of North India. The study group (n = 86) was given 200-mg mifepristone tablets on the 16th day of the menstrual cycle. The control group (n = 92) received combined oral contraceptive (COC) as per protocol. Subjects were followed for drug compliance, satisfaction, side effects, and failure. RESULTS: Acceptability of mifepristone was significantly higher in educated population (P < .001), with fewer side effects (P = .001), good satisfaction (P < .001), and higher compliance rate (P = .05). The oral contraceptive pill group had higher adverse biochemical parameters. CONCLUSION: Mifepristone can be used as a monthly contraceptive pill effectively.
Mukta Agarwal; Vinita Das; Anjoo Agarwal; Amita Pandey; Deepali Srivastava
Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-11-21
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  200     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-20     Completed Date:  2009-05-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e27-9     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, CSM Medical University (Upgraded King George's Medical University), Lucknow, UP, India.
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MeSH Terms
Case-Control Studies
Contraception / methods*
Contraceptives, Oral, Synthetic / administration & dosage*,  adverse effects
Follow-Up Studies
Menstrual Cycle
Mifepristone / administration & dosage*,  adverse effects
Patient Satisfaction*
Prospective Studies
Young Adult
Reg. No./Substance:
0/Contraceptives, Oral, Synthetic; 84371-65-3/Mifepristone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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