| Evaluation of mifepristone as a once a month contraceptive pill. | |
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MedLine Citation:
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PMID: 19026402 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to assess the efficacy and safety of mifepristone as a contraceptive pill. STUDY DESIGN: A prospective case-control study was conducted in a tertiary care center of North India. The study group (n = 86) was given 200-mg mifepristone tablets on the 16th day of the menstrual cycle. The control group (n = 92) received combined oral contraceptive (COC) as per protocol. Subjects were followed for drug compliance, satisfaction, side effects, and failure. RESULTS: Acceptability of mifepristone was significantly higher in educated population (P < .001), with fewer side effects (P = .001), good satisfaction (P < .001), and higher compliance rate (P = .05). The oral contraceptive pill group had higher adverse biochemical parameters. CONCLUSION: Mifepristone can be used as a monthly contraceptive pill effectively. |
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Authors:
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Mukta Agarwal; Vinita Das; Anjoo Agarwal; Amita Pandey; Deepali Srivastava |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't Date: 2008-11-21 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 200 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-04-20 Completed Date: 2009-05-18 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: e27-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, CSM Medical University (Upgraded King George's Medical University), Lucknow, UP, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Case-Control Studies Contraception / methods* Contraceptives, Oral, Synthetic / administration & dosage*, adverse effects Female Follow-Up Studies Humans India Menstrual Cycle Mifepristone / administration & dosage*, adverse effects Patient Satisfaction* Prospective Studies Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Contraceptives, Oral, Synthetic; 84371-65-3/Mifepristone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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