Document Detail


Evaluation of mercury toxicity by some cytological indices in leucocyte cultures.
MedLine Citation:
PMID:  16121717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The genotoxicity induced by different levels of inorganic mercury was evaluated by chromosome metaphase analysis in human leucocytes, treated in vitro for 72 hr. Mitotic index gradually decreased with an increase in concentration of mercury but the reverse phenomenon was observed with respect to chromosomal aberration due to its probable interaction with protein and DNA.
Authors:
A Halder; M Patra; M De
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  43     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  2005 Aug 
Date Detail:
Created Date:  2005-08-26     Completed Date:  2005-09-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  India    
Other Details:
Languages:  eng     Pagination:  737-9     Citation Subset:  IM    
Affiliation:
Department of Genetics, Vivekananda Institute of Medical Sciences, Ramakrishna Mission Seva Pratishthan, 99, Sarat Bose Road, Kolkata 700 026, India. ajantahaldar@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cells, Cultured
Child
Child, Preschool
Chromosome Aberrations / chemically induced*
Dose-Response Relationship, Drug
Humans
Infant
Leukocytes / drug effects*,  metabolism
Mercuric Chloride / toxicity*
Middle Aged
Chemical
Reg. No./Substance:
7487-94-7/Mercuric Chloride

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