Document Detail


Evaluation of lipid profile in adolescents during long-term use of combined oral hormonal contraceptives.
MedLine Citation:
PMID:  15707561     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The study evaluated the effects of the long-term use of a combined oral hormonal contraceptive containing 30 microg ethinyl estradiol and 75 microg gestodene in adolescents. Thirty-three volunteers, aged from 14 to 19 years, who used the oral contraceptive for three consecutive years, were studied. Evaluation of total cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C) and triglycerides was made before use and after 1, 2 and 3 years. During the 3-year study period, total cholesterol, HDL-C, LDL-C and triglyceride levels were significantly higher than previous measurements, but average values did not exceed the normal range. Compared to the first year, the second- and third-year cholesterol, HDL-C, LDL-C and triglyceride levels were not significantly different.
Authors:
Christina Aparecida Falbo Guazzelli; Prescilla Chow Lindsey; Fabio Fernando de Araújo; Márcia Barbieri; Carlos Alberto Petta; Jose Mendes Aldrighi
Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  Contraception     Volume:  71     ISSN:  0010-7824     ISO Abbreviation:  Contraception     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-14     Completed Date:  2005-12-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0234361     Medline TA:  Contraception     Country:  United States    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
Affiliation:
Family Planning Clinic, Department of Obstetrics and Gynecology, Universidade Federal de São Paulo, São Paulo CEP 09090050, Brazil. guazzelli.toco@epm.br
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cholesterol, HDL / blood,  metabolism
Cholesterol, LDL / blood,  metabolism
Contraceptives, Oral, Combined / administration & dosage,  pharmacology*
Ethinyl Estradiol / administration & dosage,  pharmacology
Female
Humans
Lipid Metabolism / drug effects*
Lipids / blood
Norpregnenes / administration & dosage,  pharmacology
Time Factors
Treatment Outcome
Triglycerides / blood,  metabolism
Chemical
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Contraceptives, Oral, Combined; 0/Lipids; 0/Norpregnenes; 0/Triglycerides; 57-63-6/Ethinyl Estradiol; 60282-87-3/Gestodene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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