Document Detail


Evaluation of left ventricular systolic and diastolic function in patients with atrioventricular re-entrant tachycardia treated by radiofrequency current ablation.
MedLine Citation:
PMID:  18468204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Little is known about the long-term influence of radiofrequency current ablation (RFCA) on left ventricular (LV) systolic and diastolic function in patients with atrioventricular re-entrant tachycardia (AVRT). METHOD: The study group consisted of 65 patients (33 M, mean age 39 +/- 11 y) with WPW syndrome and recurrent episodes of AVRT without any concomitant diseases. The control group consisted of 50 age-matched healthy volunteers. In both study and control groups transthorasic echocardiography (TTE) and Doppler were performed in order to assess LV systolic and diastolic function. In WPW patients TTE was followed by electrophysiology study and RFCA. TTE was repeated in 6-months time in the study group. RESULTS: At 6-month follow-up a decrease in LV end-systolic diameters (1.77 +/- 0.22 vs. 1.67 +/- 0.22 cm/m2, P < 0.001) and volumes (20 +/- 6 vs. 17 +/- 5 ml, P < 0.001) and an increase in LV FS (33 +/- 6 vs. 37 +/- 5%, P < 0.001), EF (54 +/- 6 vs. 60 +/- 5%, P < 0.001), IVS (44 +/- 13 vs. 49 +/- 14%, P < 0.05) and LV PW thickening (58 +/- 19 vs. 62 +/- 16%, P < 0.05) was found. Doppler analysis revealed an increase in E wave (78 +/- 17 vs. 82 +/- 14 cm/s, P < 0.001), E/A ratio (1.14 +/- 0.37 vs. 1.33 +/- 0.24, P < 0.001) and a decrease in A wave (68 +/- 19 vs. 63 +/- 12 cm/s, P < 0.05), DT (219 +/- 33 vs. 180 +/- 20 ms, P < 0.001 ), IVRT (105 +/- 13 vs. 88 +/- 13 ms, P < 0.001), AR (26 +/- 8 vs. 18 +/- 12 cm/s, P < 0.001 ) and difference between duration of AR and A waves (5 +/- 24 vs. -12 +/- 21 ms, P < 0.001). No significant differences in regard to LV systolic and diastolic variables were found between patients and controls post RFCA. CONCLUSION: RFCA of accessory pathway in patients with WPW syndrome and AVRT is associated with improvement of LV systolic and diastolic function.
Authors:
Agata Duszanska; Radosław Lenarczyk; Oskar Kowalski; Witold Streb; Tomasz Kukulski; Zbigniew Kalarus
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta cardiologica     Volume:  63     ISSN:  0001-5385     ISO Abbreviation:  Acta Cardiol     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-05-12     Completed Date:  2008-07-31     Revised Date:  2009-06-11    
Medline Journal Info:
Nlm Unique ID:  0370570     Medline TA:  Acta Cardiol     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  221-7     Citation Subset:  IM    
Affiliation:
Department of Cardiology, Medical University of Silesia in Katowice, Silesian Centre for Heart Disease, Zabrze, Poland. agataduszanska@op.pl
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MeSH Terms
Descriptor/Qualifier:
Adult
Diastole
Echocardiography, Doppler / methods
Echocardiography, Transesophageal / methods
Female
Follow-Up Studies
Humans
Male
Myocardial Contraction / physiology*
Prognosis
Retrospective Studies
Severity of Illness Index
Systole
Tachycardia, Atrioventricular Nodal Reentry / physiopathology*,  surgery,  ultrasonography
Time Factors
Ventricular Function, Left / physiology*

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