| Evaluation of left ventricular systolic and diastolic global function: peak positive and negative myocardial velocity gradients in M-mode Doppler tissue imaging. | |
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MedLine Citation:
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PMID: 11884251 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To evaluate a new indicator of left ventricular global function: Myocardial velocity gradient (MVG) M-mode Doppler tissue imaging (DTI). BACKGROUND: MVG is a new indicator of regional left ventricular function and global left ventricular diastolic function. However, it is unclear whether MVG also is an indicator of left ventricular global function in comparison with invasive indices. METHODS: We performed conventional imaging and M-mode DTI in 85 subjects and calculated MVG at the posterior wall. We obtained satisfactory images in 65 subjects, who we divided into three groups: Noninvasive study group, invasive study group, and hemodialysis group. The noninvasive study group was divided into three subgroups (a younger normal subgroup, an older normal subgroup, and a cardiomyopathy subgroup), and MVG was compared with indices of conventional imaging. In the invasive study group, we compared MVG and indices of conventional imaging with hemodynamic data (peak positive and negative dp/dt, and the time constant T) using a high fidelity micromanometer-tipped catheter. In the hemodialysis group, we compared indices before hemodialysis with those after hemodialysis. RESULTS: Peak positive MVG correlated well with peak positive dp/dt (r = 0.79), and this did not change with hemodialysis (P = 0.87). Peak negative MVG also correlated well with peak positive dp/dt and the time constant T (r = 0.88 and r = 0.80), and this did not change with hemodialysis (P = 0.97). CONCLUSIONS: Peak positive and negative MVG are sensitive and load-insensitive indicators of left ventricular function. |
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Authors:
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Yoshiki Ueno; Yasuyuki Nakamura; Yasunori Ohbayashi; Masahiko Kinoshita |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Echocardiography (Mount Kisco, N.Y.) Volume: 19 ISSN: 0742-2822 ISO Abbreviation: Echocardiography Publication Date: 2002 Jan |
Date Detail:
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Created Date: 2002-03-08 Completed Date: 2002-04-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8511187 Medline TA: Echocardiography Country: United States |
Other Details:
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Languages: eng Pagination: 15-25 Citation Subset: IM |
Affiliation:
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The First Department of Internal Medicine, Shiga University Of Medical Science, Tsukinowa, Seta, Otsu, Shiga, 520-2192, Japan. nakamura@suncuore.shiga-med.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Analysis of Variance Cardiomyopathy, Dilated / physiopathology, ultrasonography* Diastole / physiology Echocardiography, Doppler, Color / methods* Female Humans Kidney Failure, Chronic / therapy Linear Models Male Middle Aged Myocardial Contraction / physiology* Probability Prognosis Reference Values Renal Dialysis Sensitivity and Specificity Stroke Volume Systole / physiology Ventricular Dysfunction, Left / physiopathology, ultrasonography* Ventricular Function, Left / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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