Document Detail

Evaluation of left ventricular rotation in obese subjects by velocity vector imaging.
MedLine Citation:
PMID:  20190270     Owner:  NLM     Status:  In-Process    
AIMS: Obesity is a well-known risk factor in the development of cardiovascular disease. We hypothesize that early left ventricular (LV) dysfunction secondary to obesity could be signalled by abnormal LV rotation.
METHODS AND RESULTS: This prospective study examined 60 subjects divided into two groups: obese group with body mass index (BMI) >or=30 and control group with BMI <25. The peak rotation, twist, and torsion of the left ventricle were studied in obese and control subjects, using velocity vector imaging. Age and gender were comparable between the two groups. Obese subjects had higher BMI, waist circumference, fasting glucose, triglycerides, systolic and diastolic blood pressure, low-density lipoprotein cholesterol, and lower high-density lipoprotein cholesterol (P < 0.05). In obese subjects, LV mass and LV mass index were increased, and the ratio of mitral early and late diastolic filling velocity was decreased (P < 0.05). In obese subjects, the peak twist and torsion of the left ventricle displayed a lower trend, and the peak rotation of the left ventricle apex decreased significantly (3.81 +/- 2.09 degrees vs. 5.77 +/- 3.27 degrees , P < 0.001).
CONCLUSION: Obesity was associated with changes in LV rotation. Velocity vector imaging is a feasible and reproducible echocardiographic technique for the detection of early subclinical LV dysfunction.
Yan Deng; Mohsen S Alharthi; Venkata R Thota; Lixue Yin; Chunmei Li; Usha R Emani; Krishnaswamy Chandrasekaran; Bijoy Khandheria; Farouk Mookadam
Publication Detail:
Type:  Journal Article     Date:  2010-02-27
Journal Detail:
Title:  European journal of echocardiography : the journal of the Working Group on Echocardiography of the European Society of Cardiology     Volume:  11     ISSN:  1532-2114     ISO Abbreviation:  Eur J Echocardiogr     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890618     Medline TA:  Eur J Echocardiogr     Country:  England    
Other Details:
Languages:  eng     Pagination:  424-8     Citation Subset:  IM    
Department of Cardiovascular Ultrasound and Non-invasive Cardiology, Sichuan Academy of Medical Science, Sichuan Provincial People's Hospital, Sichuan, China.
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Comment In:
Eur J Echocardiogr. 2010 Jun;11(5):422-3   [PMID:  20190271 ]

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