Document Detail

Evaluation of left ventricular myocardial perfusion and function using gated SPECT in patients with hypertrophic obstruction cardiomyopathy following percutaneous transluminal septal myocardial ablation.
MedLine Citation:
PMID:  24681766     Owner:  NLM     Status:  Publisher    
OBJECTIVE: This study was designed to evaluate the left ventricular myocardial perfusion and function in hypertrophic obstruction cardiomyopathy patients following percutaneous transluminal septal myocardial ablation (PTSMA) using rest single-photon emission computed tomography (SPECT) myocardial perfusion imaging.
PATIENTS AND METHODS: Thirty-five patients (24 men and 11 women, 48±11 years old) with hypertrophic obstruction cardiomyopathy underwent rest-gated Tc-MIBI SPECT imaging 4±10 days before (baseline) and 4.7±1.0 days (short-term) and 15.5±8.2 months (mid-term) after PTSMA. Semiquantitative and QGS quantitative evaluations of perfusion and function were carried out in 17 left ventricular segments.
RESULTS: Myocardial perfusion of the septum following PTSMA was significantly reduced compared with baseline in all patients (P<0.05), but the myocardial perfusion in the basal septum was significantly higher at mid-term compared with short-term following PTSMA (P<0.05). Left ventricular ejection fraction was significantly decreased following PTSMA (P<0.05). Regional wall motion assessed in the basal anterior, basal septum, and basal inferior areas following PTSMA was significantly reduced compared with baseline (P<0.05), and wall thickening of the interventricular septum was decreased following PTSMA (P<0.05).
CONCLUSION: Rest-gated SPECT imaging can be used to assess left ventricular myocardial perfusion and function and to investigate the efficacy of PTSMA during follow-up.
Ling Zhang; Rong Liu; Shu-Bin Qiao; Xiao-Xin Sun; Zuo-Xiang He; Yue-Qin Tian
Related Documents :
11887276 - Post myocardial infarction treatment in the older adult.
2741826 - Predictive value of indium-111 antimyosin uptake for improvement of left ventricular wa...
11590876 - Cardiovascular drugs and the risk of death in acute myocardial infarction in northern s...
16278116 - Acute coronary syndromes in the emergency department: diagnostic characteristics, tests...
11411756 - Fibrosis and ischemia: the real risks in hypertensive heart disease.
15516236 - Influence of retrograde flushing via the caval vein on the post-reperfusion syndrome in...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-27
Journal Detail:
Title:  Nuclear medicine communications     Volume:  -     ISSN:  1473-5628     ISO Abbreviation:  Nucl Med Commun     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-3-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Evaluation of delineation of image details in semiconductor PET utilizing the normalized mutual info...
Next Document:  Does CEA and CA 19-9 combined increase the likelihood of 18F-FDG in detecting recurrence in colorect...