Document Detail

Evaluation of left ventricular hypertrophy in patients requiring permanent pacing.
MedLine Citation:
PMID:  20696682     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Hypertension may lead to left ventricular hypertrophy, fibrosis and degeneration of the conduction system. Our aim was to study the association of hypertrophy with certain arrhythmias such as complete atrioventricular block (AVB) and symptomatic sick sinus syndrome (SSS) that require implantation of permanent pacemaker.
METHODS: We studied 130 patients that had been given a pacemaker because of complete AVB, 130 patients that had been given a pacemaker because of symptomatic SSS and 45 patients without cardiac conduction disturbances. In order to estimate left ventricular hypertrophy, indexes of relative wall thickness (RWT) and left ventricular mass (LVM) were evaluated by echocardiography.
RESULTS: We observed significant association between complete AVB and abnormal values of echocardiographic indexes.
CONCLUSIONS: Our results lend further support to the hypothesis that complete AVB is associated with left ventricular hypertrophy. This hypothesis is enhanced by the observation that the majority of patients with complete AVB were hypertensive.
Alexandros Alexopoulos; Anastasia Perpinia; Nikolaos Michelakakis; Charalambos Kossyvakis; Spyridon Deftereos; Vlassios Pyrgakis
Publication Detail:
Type:  Journal Article     Date:  2010-08-09
Journal Detail:
Title:  Therapeutic advances in cardiovascular disease     Volume:  4     ISSN:  1753-9455     ISO Abbreviation:  Ther Adv Cardiovasc Dis     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-05     Completed Date:  2011-01-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101316343     Medline TA:  Ther Adv Cardiovasc Dis     Country:  England    
Other Details:
Languages:  eng     Pagination:  295-9     Citation Subset:  IM    
Department of Cardiology, Athens General Hospital, Mesogeion Avenue, 154, 15669 Athens, Greece.
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MeSH Terms
Atrioventricular Block / epidemiology*,  therapy
Cardiac Pacing, Artificial / statistics & numerical data*
Hypertension / epidemiology*
Hypertrophy, Left Ventricular / epidemiology*,  ultrasonography
Middle Aged
Risk Factors
Sick Sinus Syndrome / epidemiology*,  therapy

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