Document Detail


Evaluation of laboratory monitoring alerts within a computerized physician order entry system for medication orders.
MedLine Citation:
PMID:  16834525     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Errors involving medication use are common. Computerized physician order entry (CPOE) can improve prescribing practices. Few studies have examined the effect of CPOE in combination with decision support tools on prescribing practices in the outpatient setting. Less is known about prescribers' adherence to laboratory monitoring recommendations. OBJECTIVE: To evaluate if reminders presented during CPOE for medications would increase physicians' compliance with guidelines for laboratory monitoring at initiation of therapy. STUDY DESIGN: Randomized prospective intervention study. METHODS: Two hundred seven primary care physicians in a group-model managed care organization were randomized to receive or not receive drug laboratory monitoring alerts within the CPOE system. Adherence to laboratory monitoring recommendations for patients prescribed selected medications was compared between physician groups. RESULTS: There was no significant difference between the control and intervention group physicians in the overall rate of compliance with ordering the recommended laboratory monitoring for patients prescribed study medications. Laboratory monitoring was performed as recommended 56.6% of the time in the intervention group compared with 57.1% of the time in the control group (P = .31). In cases in which a statistically significant difference was demonstrated, improved compliance favored the intervention group (eg, 71.2% vs 62.3% [P = .003] for gemfibrozil and 75.7% vs 73.9% [P = .05] for statins). CONCLUSIONS: As CPOE becomes more prevalent, additional research is needed to determine effective decision support tools. These findings then should be communicated to the developers and users of computerized medical record systems.
Authors:
Ted E Palen; Marsha Raebel; Ella Lyons; David M Magid
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The American journal of managed care     Volume:  12     ISSN:  1088-0224     ISO Abbreviation:  Am J Manag Care     Publication Date:  2006 Jul 
Date Detail:
Created Date:  2006-07-12     Completed Date:  2006-09-15     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9613960     Medline TA:  Am J Manag Care     Country:  United States    
Other Details:
Languages:  eng     Pagination:  389-95     Citation Subset:  H    
Affiliation:
Clinical Research Unit, Colorado Permanente Medical Group, PO Box 378066, Denver, CO 80237-8066, USA. ted.e.palen@kp.org
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Adverse Drug Reaction Reporting Systems
Aged
Aged, 80 and over
Ambulatory Care / standards
Clinical Laboratory Information Systems*
Decision Support Systems, Clinical*
Drug Monitoring / methods*
Female
Guideline Adherence
Humans
Male
Managed Care Programs / standards
Medical Order Entry Systems*
Medical Records Systems, Computerized
Middle Aged
Primary Health Care / standards
Reminder Systems*
Safety Management
Treatment Outcome
United States
Grant Support
ID/Acronym/Agency:
U18 HS11843/HS/AHRQ HHS
Comments/Corrections
Comment In:
Am J Manag Care. 2006 Jul;12(7):369-70   [PMID:  16834523 ]
Am J Manag Care. 2006 Sep;12(9):563; author reply 563   [PMID:  16961445 ]
Am J Manag Care. 2006 Jul;12(7):365-6   [PMID:  16834522 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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