| Evaluation of ischemic heart disease on a 1.5 Tesla scanner: combined first-pass perfusion and viability study. | |
| | |
MedLine Citation:
|
PMID: 16012398 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: We implemented a fast gradient echo (GRE) sequence with an echo-planar imaging (EPI) read-out (FGRE-ET) to conduct myocardial perfusion studies on a conventional scanner. The accuracy of combined perfusion and viability studies is evaluated in comparison with coronary angiography (CAG). MATERIALS AND METHODS: We enrolled 33 patients suspected of having coronary artery disease in this study. Short-axis perfusion images of the left ventricles were acquired following intravenous bolus injection of gadolinium-DTPA (0.05 mml/kg), both after myocardial loading by dipyridamole (0.56 mg/kg) and at rest. Viability studies were obtained using an inversion-recovery FGRE sequence. Radiologists performed blinded film readings. The findings with perfusion and the viability studies were compared with CAG on a segment-to-segment basis corresponding to the coronary arteries' territories. Stenosis equal to or greater than 75% in diameter was considered significant on CAG. The results were also compared with single photon emission computed tomography (SPECT) in 23 patients. RESULTS: The combination of perfusion and viability studies showed 85.7% sensitivity, 88.9% specificity, and 87.2% accuracy in comparison with CAG. SPECT revealed respective rates of 71.7%, 78.3%, and 73.9% in 23 patients of this group. CONCLUSION: Myocardial perfusion studies using FGRE-ET were feasible and accurate, even on a conventional scanner. |
| | |
Authors:
|
Shigeo Okuda; Akihiro Tanimoto; Toru Satoh; Jun Hashimoto; Hiroshi Shinmoto; Nobuya Higuchi; Atsushi Nozaki; Sachio Kuribayashi |
Related Documents
:
|
21069488 - The role of myocardial perfusion imaging in evaluating patients with myocardial bridging. 21907948 - Usefulness of electrocardiographic qt interval to predict left ventricular diastolic dy... 3202208 - Separation of rate of left ventricular relaxation from chamber stiffness in rats. 22276258 - Screening for coronary artery disease in patients with type 2 diabetes mellitus: an evi... 10755538 - Incidence, progression and functional significance of cardiac allograft vasculopathy af... 6869208 - Subacute left ventricular free wall rupture following acute myocardial infarction: beds... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Radiation medicine Volume: 23 ISSN: 0288-2043 ISO Abbreviation: Radiat Med Publication Date: 2005 Jun |
Date Detail:
|
Created Date: 2005-07-13 Completed Date: 2005-10-14 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8412264 Medline TA: Radiat Med Country: Japan |
Other Details:
|
Languages: eng Pagination: 230-5 Citation Subset: IM |
Affiliation:
|
Department of Diagnostic Radiology, Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Coronary Angiography Dipyridamole / diagnostic use Female Gadolinium DTPA / diagnostic use Humans Magnetic Resonance Imaging / methods* Male Middle Aged Myocardial Ischemia / diagnosis*, radiography Sensitivity and Specificity Tomography, Emission-Computed, Single-Photon |
| Chemical | |
Reg. No./Substance:
|
58-32-2/Dipyridamole; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiovascular gas on non-traumatic postmortem computed tomography (PMCT): the influence of cardiopu...
Next Document: Aortic compliance in patients with aortic regurgitation: evaluation with magnetic resonance imaging.