Document Detail

Evaluation of iodine, iron, and selenium in biological samples of thyroid mother and their newly born babies.
MedLine Citation:
PMID:  20716473     Owner:  NLM     Status:  In-Process    
BACKGROUND: There is accumulating facts that the metabolism of essential trace elements is altered in thyroid patients.
AIM: The aim of present study was to compare the status of essential trace elements, iodine, iron (Fe), and selenium (Se) in biological samples (serum and urine) of goitrous mothers (age ranged 30-40) and their newly born infants (n=76). An age matched 68 non-goitrous mothers and their infants, residing in the same locality, were selected as referents. For a comparative study, the biological samples of non-goitrous and goitrous pregnant and non pregnant female subjects of the same age group and socio-economic status were also analyzed.
METHODS: The Fe and Se concentrations in biological samples were determined by a flame and hydride generation atomic absorption spectrometry respectively, while iodine was measured by iodide-ion selective electrode, prior to microwave assisted acid digestion. The validity and accuracy of the methodology was checked by certified reference materials.
RESULTS: The mean values of iodine, Fe and Se in serum and urine samples of thyroid mothers and their infants were significantly lower as compared to the referent mothers-infants pairs (p<0.01).
CONCLUSIONS: The deficiencies of essential trace elements may adversely affect the health of women and their neonates.
Tasneem Gul Kazi; Ghulam Abbas Kandhro; Sirajuddin; Hassan Imran Afridi; Jameel Ahmed Baig; Abdul Qadir Shah; Sham Kumar Wadhwa; Sumaira Khan; Nida Fatima Kolachi; Hafeez-ur-Rahman Shaikh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-15
Journal Detail:
Title:  Early human development     Volume:  86     ISSN:  1872-6232     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  649-55     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
National Centre of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan.
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