Document Detail

Evaluation of infectious episodes in neonates using a new procedure for the nitroblue tetrazolium test.
MedLine Citation:
PMID:  7056193     Owner:  NLM     Status:  MEDLINE    
A new procedure for the NBT slide test for peripheral blood neutrophils has been tested. 255 neonates were studied of which 63 served as control cases. Among the 114 term infants, 37 were patently infected, 30 suspicious and 47 non-infected. The latter did not significantly differ from control cases, whereas suspicious and infected infants were credited with significantly higher NBT scores. 78 infants were preterm, 31 of which were patently infected, 22 suspicious and 25 non-infected. NBT scores of infected and suspicious infants were significantly higher than those of non-infected infants, but, as previously reported, scores of preterm infants were systematically and significantly lower than those of full-term infants of the same bacteriological class. Threshold values are suggested; they could represent an accurate diagnostic aid in the early differentiation of healthy infants from high-risk infants regarding bacterial infections.
B Dalens; M J Bezou; P Travade; M Coulet; J P Haberer; G Vanneuville
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Early human development     Volume:  6     ISSN:  0378-3782     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-04-12     Completed Date:  1982-04-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  15-23     Citation Subset:  IM    
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MeSH Terms
Bacterial Infections / blood,  diagnosis*
Infant, Newborn
Infant, Newborn, Diseases / blood,  diagnosis*
Infant, Premature
Neutrophils / metabolism*
Nitroblue Tetrazolium / metabolism*
Tetrazolium Salts / metabolism*
Reg. No./Substance:
0/Tetrazolium Salts; 298-83-9/Nitroblue Tetrazolium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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