Document Detail

Evaluation of immunocompetence and nutritional status in patients with bulimia nervosa.
MedLine Citation:
PMID:  8416667     Owner:  NLM     Status:  MEDLINE    
Nutritional status of patients suffering from bulimia nervosa was evaluated by anthropometric, hematological, and immunological parameters in comparison with a healthy control group. Anthropometry showed no signs of malnutrition in either group. Bulimic patients showed a significant decrease in most of the routine clinical indexes related to red blood cells. Lymphocyte subsets CD2 and CD4 in bulimic patients were lower than in controls, whereas CD8 remained unmodified, leading to a lower CD4:CD8 in bulimic patients. The decreases in CD2 and CD4 numbers might be linked to an impaired cell-mediated immune function, as evaluated by the response to skin tests. The B lymphocyte subset was increased in the bulimic group. Innate immunity was impaired in the bulimic patients. Although anthropometric and most of the routine clinical parameters were within the normal range, these results might suggest that the depleted immune function accounts for a subclinical malnutrition status in bulimic patients.
A Marcos; P Varela; I Santacruz; A Muñoz-Vélez
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of clinical nutrition     Volume:  57     ISSN:  0002-9165     ISO Abbreviation:  Am. J. Clin. Nutr.     Publication Date:  1993 Jan 
Date Detail:
Created Date:  1993-01-21     Completed Date:  1993-01-21     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0376027     Medline TA:  Am J Clin Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  65-9     Citation Subset:  AIM; IM; X    
Institute de Nutricion y Bromatologia (CSIC), Ciudad Universitaria, Madrid, Spain.
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MeSH Terms
Bulimia / blood,  complications*,  immunology
CD4-CD8 Ratio
Complement System Proteins / analysis
Erythrocyte Indices
Hypersensitivity, Delayed
Immunity, Cellular
Immunoglobulins / blood
Leukocyte Count
Nutrition Disorders / etiology*
Nutritional Status*
Reg. No./Substance:
0/Immunoglobulins; 9007-36-7/Complement System Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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