Document Detail


Evaluation of a high-dose dexamethasone-eluting stent.
MedLine Citation:
PMID:  15246899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This study evaluated the safety and efficacy of a dexamethasone-eluting stent with a special high dexamethasone-loading dose for treatment of de novo coronary lesions in 30 patients. Eight patients had in-stent restenosis (restenosis rate 31%) at 6-month follow-up, and the in-stent late lumen loss was 0.96 +/- 0.63 mm due to an average intimal hyperplasia area obstruction of 32 +/- 21%, indicating that high-dose dexamethasone-loaded stents do not significantly reduce neointimal proliferation.
Authors:
Rainer Hoffmann; Roswitha Langenberg; Peter Radke; Andreas Franke; Rüdiger Blindt; Jan Ortlepp; Jeff J Popma; Christian Weber; Peter Hanrath
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  94     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-07-12     Completed Date:  2004-08-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  193-5     Citation Subset:  AIM; IM    
Affiliation:
Medical Clinic I, University Hospital Aachen, Germany. RHoffman@UKAACHEN.de
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MeSH Terms
Descriptor/Qualifier:
Adult
Anti-Inflammatory Agents / administration & dosage*
Coronary Angiography
Coronary Restenosis / prevention & control*,  radiography,  ultrasonography
Dexamethasone / administration & dosage*
Female
Humans
Male
Pilot Projects
Prosthesis Design
Stents*
Ultrasonography, Interventional
Chemical
Reg. No./Substance:
0/Anti-Inflammatory Agents; 50-02-2/Dexamethasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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