| Evaluation of hemodynamics: comparison of vacuum and mechanical stabilization in the beating heart. | |
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MedLine Citation:
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PMID: 12928204 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Hemodynamic instability remains a prominent concern for surgeons performing coronary surgery without cardiopulmonary bypass. The purpose of this study was to further elucidate the mechanism of hemodynamic instability by comparing vacuum stabilization to mechanical stabilization. METHODS: Four 60-kg swine were placed under general anesthesia. A median sternotomy incision was made, and baseline hemodynamic measurements were recorded. Mechanical and vacuum stabilization of the circumflex distribution were alternately compared with repeated baseline measurements in a counterbalanced method, and 32 experiments were conducted. RESULTS: There were significant differences between baseline hemodynamics and stabilized hemodynamics for mechanical stabilization versus vacuum stabilization, respectively, for the following parameters: blood pressure (mean decrement), -32.18% (P =.0028) versus -31.3% (P =.0006); cardiac output, -31.03% (P =.0046) versus -35.2% (P =.03); and mixed venous oxygen saturation, -29.8% (P =.008) versus -27.4% (P =.0004). There were no statistical differences between mechanical and vacuum stabilization when their decremental effects on baseline hemodynamics were compared with each other for any of the measured variables. CONCLUSIONS: The mechanisms of hemodynamic compromise during coronary stabilization remain to be fully elucidated. Our study demonstrates no statistical difference between vacuum and mechanical stabilization on the measured hemodynamic values. More sophisticated studies involving detailed analysis of motion and geometry are required so that technical solutions to hemodynamic instability can be developed. |
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Authors:
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Daniel J Beckman; Karen Bumb; Maria Bandy; Maria Evans; Cindy Romanyk |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The heart surgery forum Volume: 6 ISSN: 1522-6662 ISO Abbreviation: Heart Surg Forum Publication Date: 2003 |
Date Detail:
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Created Date: 2003-08-20 Completed Date: 2003-12-03 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100891112 Medline TA: Heart Surg Forum Country: United States |
Other Details:
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Languages: eng Pagination: 220-3 Citation Subset: IM |
Affiliation:
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CorVasc and Methodist Hospital, Indianapolis, Indiana, USA. danbeckman@comcast.net |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / physiology Coronary Artery Bypass / adverse effects*, methods Hemodynamics / physiology* Swine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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