Document Detail

Evaluation of hemodynamic changes by use of phase-contrast MRI for patients with interstitial pneumonia, with special focus on blood flow reduction after breath-holding and bronchopulmonary shunt flow.
MedLine Citation:
PMID:  23255185     Owner:  NLM     Status:  Publisher    
PURPOSE: The purpose of this study was to determine the effects of interstitial pneumonia on pulmonary, systemic, and bronchopulmonary shunt flow. MATERIALS AND METHODS: Phase-contrast flow measurements in the ascending aorta and pulmonary trunk were performed during free breathing and inspiratory breath-holding by use of a 1.5 T MR scanner. The study population comprised 11 patients with interstitial pneumonia and 15 healthy volunteers. Absolute blood flow, bronchopulmonary shunt flow, and difference in flow between normal breathing and breath-holding were compared between the groups. RESULTS: Both pulmonary and systemic blood flow during both breathing patterns in patients were significantly reduced compared with the volunteers (p < 0.05). However, bronchopulmonary shunt flow and reduction of systemic and pulmonary artery flow did not differ between groups. CONCLUSION: Interstitial pneumonia reduces both pulmonary and systemic blood flow, but it does not affect the amount of flow reduction during breath-holding. The bronchopulmonary shunt was not increased in interstitial pneumonia patients, probably because of stiffness of the bronchial arteries.
Nanae Tsuchiya; Yuichiro Ayukawa; Sadayuki Murayama
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-20
Journal Detail:
Title:  Japanese journal of radiology     Volume:  -     ISSN:  1867-108X     ISO Abbreviation:  Jpn J Radiol     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101490689     Medline TA:  Jpn J Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Radiology, Graduate School of Medical Science, University of the Ryukyus, 207, Uehara, Nishighara-cho, Nakagami-Gun, Okinawa, 903-0215, Japan,
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