Document Detail

Evaluation of hearing organ in patients with Turner syndrome.
MedLine Citation:
PMID:  18343510     Owner:  NLM     Status:  MEDLINE    
Hearing loss and middle ear diseases are often reported in some of Turner patients. In most of the reports hearing organ was evaluated with the use of subjective methods. The aim of the work was subjective and objective evaluation of hearing organ with an attempt to set the correlation between the results and the genotype of the patients with Turner syndrome (Ts). MATERIAL: 51 Ts patients aged 14.3 years on average. There were 29 girls with monosomy X and 22 having mosaicism. A detailed medical history was taken in each case with attention given to the hearing loss risk factors. METHOD: Physical ENT examination, hearing evaluation: pure tone audiometry, impedance audiometry, distortion products otoacoustic emissions (DPOAEs), brain auditory evoked potentials (BAEP). The control group consisted of 30 healthy patients. RESULTS: Recurrent acute otitis media was reported by 19.6% of Ts patients. Pure tone audiometry was improper in 36.3% ears; conductive hearing loss was present in 11.7% ears, mixed hearing loss in 5.9% ears and the moderate sensorineural hearing loss in 18.6% ears. Impedance audiometry was impaired in 14.7% of the cases. DPOAE disturbances were present in 41.4% of Ts patients, BAEP was improper in 52.0%. The percentage of the disturbances in DOPAEs and in BAEP in patients with mosaicism was 45.4 and 40.9% while in patients with monosomy 68.9 and 62%. CONCLUSIONS: Ts patients present predisposition to hearing disturbances. The disturbances seem to be connected with middle ear infections and with sensorineural hearing losses. Hearing loss in Ts women is not clinically apparent in most of the cases; this fact reflects the need of early evaluation and further monitoring of hearing organ in those patients. Sensorineural hearing loss seems to prevail in patients with 45,X genotype, so perhaps attention should be paid to this subgroup of Ts patients.
Wojciech Gawron; Beata Wikiera; Beata Rostkowska-Nadolska; Krystyna Orendorz-Fraczkowska; Anna Noczyńska
Publication Detail:
Type:  Journal Article     Date:  2008-03-17
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  72     ISSN:  0165-5876     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  2008 May 
Date Detail:
Created Date:  2008-04-02     Completed Date:  2008-09-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  575-9     Citation Subset:  IM    
University of Wroclaw, Faculty of Medicine ENT Department, ul. Chałubinskiego 2, 50-368 Wroclaw, Poland.
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MeSH Terms
Acoustic Impedance Tests
Audiometry, Pure-Tone
Evoked Potentials, Auditory, Brain Stem
Hearing Tests*
Otitis Media / complications
Otoacoustic Emissions, Spontaneous
Turner Syndrome / complications,  physiopathology*

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