Document Detail

Evaluation of geriatric patients with special reference to clinical trials of so-called nootropic drugs. I. General considerations and screening.
MedLine Citation:
PMID:  7015377     Owner:  NLM     Status:  MEDLINE    
This article, the first in a series, reviews some well-known difficulties involved in the assessment and evaluation of elderly patients. The various aims of assessment proper and of evaluation are delineated and a clear description of the specific purposes of assessment of the elderly is presented. These can differ considerably from the assessment aims for younger persons, for whom the tests were developed, thereby placing the use of traditional psychometric devices with the elderly in a doubtful position. An individualized, ecologically relevant approach is therefore suggested as an alternative. This position is further supported by the evidence that few of the standard psychometric criteria - validity, reliability, and representative reference groups - are met when standardized psychometric instruments are used with an older population. Evaluation of treatment effects, particularly drug effects, is elaborated with this evidence in mind, and the screening process is analyzed in terms of the special demands the characteristics of elderly subjects make on it. Later articles will also address the evaluation of treatment effects, concentrating on the selection of specific procedures and the assessment of baseline behavior and behavior change.
G E Gurski
Related Documents :
23192207 - Diffusion-weighted magnetic resonance imaging of the prostate: improved robustness with...
24401807 - Comparison of laser doppler and laser-assisted indocyanine green angiography prediction...
19541287 - Comparison of corneal powers obtained from 4 different devices.
12847467 - Language validation of the air transport minimum data set: time-related terms.
9835697 - Air temperature and relative humidity effects on behavioral activity of blacklegged tic...
17963537 - Omissions, conflations, and false dichotomies: conceptual and empirical problems with t...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pharmacopsychiatria     Volume:  14     ISSN:  0720-4280     ISO Abbreviation:  Pharmacopsychiatria     Publication Date:  1981 Mar 
Date Detail:
Created Date:  1981-07-23     Completed Date:  1981-07-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8103699     Medline TA:  Pharmacopsychiatria     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  51-60     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Aged* / psychology
Clinical Trials as Topic / methods*
Diagnosis, Differential
Drug Evaluation
Mental Processes / drug effects
Research Design
Socioeconomic Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  News of the discovery of acids in organic material by C.W. Scheele (author's transl)
Next Document:  A rare case of severe bilateral ectropion from scleroderma.