Document Detail


Evaluation of the genotoxicity of some natural food colours using bacterial assays.
MedLine Citation:
PMID:  7022199     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The genotoxicity of 5 natural food colours currently permitted within the European Economic Community has been studied. Ability to induce DNA damage was investigated by the use of a recently-developed E. coli rec assay. The induction of reverse mutations in E.coli WP2 trp uvrA and S.typhimurium TA1538 his rfa uvrB was detected in fluctuation assays. Both types of assays were conducted with and without metabolic activation using caecal extracts and liver microsomes from rats. Results obtained in these systems suggest that none of the colourings screened induced detectable genotoxicity.
Authors:
R B Haveland-Smith
Related Documents :
20971129 - Reconciling sensory cues and varied consequences of avian repellents.
12190619 - Hair dye-sensitized hairdressers: the cross-reaction pattern with new generation hair d...
24549199 - Sporulation of bacillus spp. within biofilms: a potential source of contamination in fo...
3723359 - Polymeric dyes: limitations in their use as reference markers in postcibal studies.
8185609 - Biodegradation of malachite green and rhodamine b by caecal microflora of rats.
24274459 - The ubiquitous nature of listeria monocytogenes clones: a large scale multilocus sequen...
15310399 - Ancestry reported by white adults with cutaneous melanoma and control subjects in centr...
8171429 - Tissue-specific differences in accumulation of stress proteins in mytilus edulis expose...
17613059 - Effects of irradiation on fungi and fumonisin b(1) in corn, and of microwave-popping on...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Mutation research     Volume:  91     ISSN:  0027-5107     ISO Abbreviation:  Mutat. Res.     Publication Date:    1981 Jul-Sep
Date Detail:
Created Date:  1981-10-25     Completed Date:  1981-10-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0400763     Medline TA:  Mutat Res     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  285-90     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Biotransformation
Cecum / metabolism
Escherichia coli / drug effects
Food Coloring Agents*
Mutagenicity Tests
Mutagens*
Rats
Salmonella typhimurium / drug effects
Chemical
Reg. No./Substance:
0/Food Coloring Agents; 0/Mutagens

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Genetic activity of actinomycin D in Saccharomyces cerevisiae but not in Escherichia coli.
Next Document:  Rat hepatic vinyl chloride metabolites induce gene conversion in the yeast strain D7RAD in vitro and...