Document Detail

Evaluation of first-trimester tricuspid regurgitation for Down syndrome screening.
MedLine Citation:
PMID:  19011492     Owner:  NLM     Status:  MEDLINE    
Screening for Down syndrome has become an integral part of prenatal care. In recent years, there has been significant interest in first-trimester screening methods. Increased nuchal translucency in the first trimester of pregnancy has been identified as a marker for chromosomal anomalies and congenital cardiac disease. In addition, research has identified a correlation between tricuspid regurgitation, diagnosed by pulsed-wave Doppler ultrasonography, in aneuploid fetuses between 11 and 13 + 6 weeks' gestation. This article provides a brief historical overview of screening for aneuploidy and examines the emerging trend and pitfalls of first-trimester screening.
Deborah Cooper McGee
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of perinatal & neonatal nursing     Volume:  22     ISSN:  1550-5073     ISO Abbreviation:  J Perinat Neonatal Nurs     Publication Date:    2008 Oct-Dec
Date Detail:
Created Date:  2008-11-17     Completed Date:  2009-02-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8801387     Medline TA:  J Perinat Neonatal Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  282-90; quiz 292-3     Citation Subset:  N    
Obstetrix Medical Group of Colorado, Perinatal Nurse Practitioner Services, Presbyterian/St. Luke's Medical Center, Denver, CO 80218, USA.
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MeSH Terms
Down Syndrome / complications,  genetics,  ultrasonography*
Evaluation Studies as Topic
Gestational Age
Mass Screening / methods*,  nursing,  trends
Nuchal Translucency Measurement
Nurse's Role
Pregnancy Trimester, First*
Reproducibility of Results
Risk Assessment
Risk Factors
Sensitivity and Specificity
Translocation, Genetic / genetics
Tricuspid Valve Insufficiency / complications,  genetics,  ultrasonography*
Ultrasonography, Doppler, Pulsed
Ultrasonography, Prenatal / methods*,  nursing,  trends

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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