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Evaluation of findings in Crouzon's syndrome.
MedLine Citation:
PMID:  12045969     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
PURPOSE. The purpose of this study was to investigate the ocular, facial and radiological signs of Crouzon's syndrome in a group of older patients who had not undergone previous craniofacial surgery. METHODS. Six cases of Crouzon's syndrome, four of whom belonged to a three-generation family, were examined systemically, ophthalmologically and roentgenographically; five of these cases were additionally evaluated with computed tomography and compared with Apert syndrome. RESULTS. On radiologic evaluation, all cases had synostosis of all cranial sutures and fontanelles and brachycephalic skulls, crowding of the upper teeth due to maxillary hypoplasia, and serious nasal septum deviation. Bilateral ethmoidal, maxillary and sphenoidal chronic sinusitis was found in 50% of cases. Three patients had hypertelorism and two others had a tendency toward hypertelorism. The typical facial appearance with shallow orbits, globe protrusion and exorbitism was present in all cases. Two of them had V-pattern exotropia while the other four were orthophoric. The single case with mental retardation had bilateral cataract. CONCLUSION. Crouzon's syndrome can present with different findings and must be evaluated multidisciplinarly.
Authors:
Ayse Gül Koçak Altintas; Fatma Gül Gül Aksoy; Cumhur S. Altintas; Inci Koçak Midillioglu; Sunay Duman
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Orbit (Amsterdam, Netherlands)     Volume:  18     ISSN:  1744-5108     ISO Abbreviation:  Orbit     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2002-Jun-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301221     Medline TA:  Orbit     Country:  -    
Other Details:
Languages:  ENG     Pagination:  247-259     Citation Subset:  -    
Affiliation:
Department of Ophthalmology, Ankara Research and Training Hospital, Ankara, Turkey
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