Document Detail

Evaluation of fetal lungs and stomach in the determination of amniotic sac infection.
MedLine Citation:
PMID:  22059459     Owner:  NLM     Status:  In-Data-Review    
This study evaluated neutrophils in fetal lung/stomach, in association with chorioamnionitis. Reports/slides from fetuses 13-24 weeks with a confirmed histologic diagnosis of placental chorioamnionitis were reviewed. There were 94 cases with no neutrophils in the lungs or stomach, and 106 with neutrophils in lungs, stomach, or both (53%). Thirteen percent showed neutrophils in the lungs only. Fetuses with no neutrophils were older than those with neutrophils in the stomach only (p = 0.008). Neutrophils in fetal lungs/stomach are common, and may confirm chorioamnionitis when the placenta is not available. Submission of gastric sections increases identification of chorioamnionitis.
Debra S Heller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Fetal and pediatric pathology     Volume:  30     ISSN:  1551-3823     ISO Abbreviation:  Fetal Pediatr Pathol     Publication Date:  2011  
Date Detail:
Created Date:  2011-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230972     Medline TA:  Fetal Pediatr Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  394-6     Citation Subset:  IM    
Department of Pathology, UMDNJ-New Jersey Medical School, Newark, New Jersey, USA.
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