| Evaluation of exercise and potassium chloride supplementation on blood pressure and nociceptive threshold in hypertensive rats. | |
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MedLine Citation:
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PMID: 20383229 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hypertensive subjects present an increased nociceptive threshold, and the lack or delay of pain perception may impede detection of angina and myocardial infarction. Nutritional interventions, like potassium chloride (KCl) diet supplementation, and exercises are common nonpharmacological indications for treating hypertension. Spontaneous hypertensive rats (SHR) and normotensive male Wistar rats were submitted to a combination of exercise and KCl diet supplementation. Exercise reduced the nociceptive threshold in SHR; however, this effect was inhibited by KCl supplementation. Exercise and KCl supplementation did not alter systolic blood pressure. Reduction of the nociceptive threshold by exercise may be important for the detection of angina and myocardial infarction in hypertensive individuals. |
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Authors:
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Giovane S Galdino; Airton M C Lopes; Valéria M Franca; Igor D G Duarte; Andrea C Perez |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Applied physiology, nutrition, and metabolism = Physiologie appliquée, nutrition et métabolisme Volume: 35 ISSN: 1715-5312 ISO Abbreviation: Appl Physiol Nutr Metab Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-04-12 Completed Date: 2010-07-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101264333 Medline TA: Appl Physiol Nutr Metab Country: Canada |
Other Details:
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Languages: eng Pagination: 184-7 Citation Subset: IM |
Affiliation:
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Department of Pharmacology, Institute of Biological Sciences, Federal University of Minas Gerais, Av. Antônio Carlos 6627, Belo Horizonte, Brazil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure / drug effects* Dietary Supplements* Disease Models, Animal Exercise Therapy* Hypertension / physiopathology, therapy* Male Pain Measurement Pain Threshold / drug effects* Physical Exertion* Potassium Chloride / administration & dosage* Rats Rats, Inbred SHR Rats, Wistar |
| Chemical | |
Reg. No./Substance:
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7447-40-7/Potassium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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