Document Detail


Evaluation of esophageal motor function in clinical practice.
MedLine Citation:
PMID:  23336590     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Esophageal motor function is highly coordinated between central and enteric nervous systems and the esophageal musculature, which consists of proximal skeletal and distal smooth muscle in three functional regions, the upper and lower esophageal sphincters, and the esophageal body. While upper endoscopy is useful in evaluating for structural disorders of the esophagus, barium esophagography, radionuclide transit studies, and esophageal intraluminal impedance evaluate esophageal transit and partially assess motor function. However, esophageal manometry is the test of choice for the evaluation of esophageal motor function. In recent years, high-resolution manometry (HRM) has streamlined the process of acquisition and display of esophageal pressure data, while uncovering hitherto unrecognized esophageal physiologic mechanisms and pathophysiologic patterns. New algorithms have been devised for analysis and reporting of esophageal pressure topography from HRM. The clinical value of HRM extends to the pediatric population, and complements preoperative evaluation prior to foregut surgery. Provocative maneuvers during HRM may add to the assessment of esophageal motor function. The addition of impedance to HRM provides bolus transit data, but impact on clinical management remains unclear. Emerging techniques such as 3-D HRM and impedance planimetry show promise in the assessment of esophageal sphincter function and esophageal biomechanics.
Authors:
C P Gyawali; A J Bredenoord; J L Conklin; M Fox; J E Pandolfino; J H Peters; S Roman; A Staiano; M F Vaezi
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society     Volume:  25     ISSN:  1365-2982     ISO Abbreviation:  Neurogastroenterol. Motil.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-22     Completed Date:  2013-09-10     Revised Date:  2013-09-24    
Medline Journal Info:
Nlm Unique ID:  9432572     Medline TA:  Neurogastroenterol Motil     Country:  England    
Other Details:
Languages:  eng     Pagination:  99-133     Citation Subset:  IM    
Copyright Information:
© 2013 Blackwell Publishing Ltd.
Affiliation:
Division of Gastroenterology, Washington University School of Medicine, St. Louis, MO, USA. cprakash@wustl.edu
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MeSH Terms
Descriptor/Qualifier:
Esophageal Motility Disorders / diagnosis*,  physiopathology*
Esophagus / physiopathology*
Humans
Manometry / methods
Comments/Corrections
Comment In:
Neurogastroenterol Motil. 2013 Sep;25(9):775   [PMID:  23701414 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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