Document Detail

Evaluation of esophageal bile reflux after total gastrectomy by gastrointestinal and hepatobiliary dual scintigraphy.
MedLine Citation:
PMID:  10211558     Owner:  NLM     Status:  MEDLINE    
Conducting the qualitative evaluation of reconstruction methods is difficult because of their complexity. The aim of the present study was to compare esophageal bile and food reflux by performing gastrointestinal and hepatobiliary dual scintigraphy (GHDS) after various methods of reconstruction following total gastrectomy. Of 17 patients studied, 4 had undergone Roux-en-Y anastomoses (R-Y); 6, jejunal pouch-Y anastomoses (P-Y); and 7, jejunal pouch interposition (P-I). GHDS was performed 1 year after surgery using 111In-diethylene triamine pentaacetic acid administered orally, and 99mTc-pyridoxyl-5-methyl tryptophan administered intravenously. Imaging data from a gamma camera were stored in and processed by a data analyzer. Three patients who had undergone R-Y and one who had undergone P-I complained of heartburn, while one who had undergone R-Y, two who had undergone P-Y, and three who had undergone P-I complained of a feeling of fullness. Esophageal bile reflux was confirmed by GHDS in four of the patients who had undergone R-Y, one who had undergone P-Y, and four who had undergone P-I. Moreover, GHDS demonstrated food retention in two patients who had undergone R-Y, five who had undergone P-Y, and four who had undergone P-I. Weight loss was closely related to the esophageal reflux of bile or food which can be accurately detected by GHDS. Despite the absence of heartburn, patients diagnosed as having bile reflux by GHDS showed poor recovery of body weight.
S Adachi; T Takeda; K Fukao
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Surgery today     Volume:  29     ISSN:  0941-1291     ISO Abbreviation:  Surg. Today     Publication Date:  1999  
Date Detail:
Created Date:  1999-06-08     Completed Date:  1999-06-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204360     Medline TA:  Surg Today     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  301-6     Citation Subset:  IM    
Department of Surgery, Institute of Clinical Medicine, University of Tsukuba, Japan.
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MeSH Terms
Anastomosis, Roux-en-Y
Bile Reflux / radionuclide imaging*
Biliary Tract / radionuclide imaging*
Digestive System / radionuclide imaging*
Gastrectomy / methods*
Gastroesophageal Reflux / radionuclide imaging*
Liver / radionuclide imaging*
Middle Aged
Pentetic Acid / diagnostic use
Postoperative Period
Treatment Outcome
Reg. No./Substance:
67-43-6/Pentetic Acid

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