| Evaluation of erectile dysfunction and associated cardiovascular risk using structured questionnaires in Chinese type 2 diabetic men. | |
| | |
MedLine Citation:
|
PMID: 20059584 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
Erectile dysfunction (ED) is not uncommon, but frequently underdiagnosed in type 2 diabetic men. In this study, we aimed to explore the frequency and severity of ED in Chinese type 2 diabetic men using a structured questionnaire. We furthermore sought to investigate the associations of ED with diabetes-related complications and metabolic indices. A consecutive cohort of 313 Chinese type 2 diabetic men aged between 25 and 76 years attending a diabetic centre were recruited between October 2006 and June 2007. Of the study population, the frequency of ED was 39.3% according to the National Institutes of Health (NIH) Consensus Conference criteria, compared with 84.3% (41.7% of them having moderate to severe ED) as diagnosed by International Index of Erectile Function (IIEF-5) questionnaire. After adjusting for potential confounding factors by multivariable logistic regression, ED defined by NIH criterion was associated with advanced age [OR = 1.05 (95% CI 1.01-1.09), p = 0.012], the presence of diabetic retinopathy [OR = 2.43 (95% CI 1.27-4.66), p = 0.008] and coronary heart disease [OR = 2.63 (95% CI 1.21-5.70), p = 0.015]. ED defined by IIEF-5 was associated with advanced age [OR = 1.12 (95% CI 1.06-1.17), p < 0.0001], use of insulin therapy [OR = 2.94 (95% CI 1.12-7.73), p = 0.029] and urinary albumin-creatinine ratio [OR = 2.29 (95% CI 1.05-5.01), p = 0.037]. In conclusion, ED was highly prevalent in Chinese type 2 diabetic men and was associated with multiple cardiovascular risk factors and complications. Advanced age, use of insulin therapy, the existence of microvascular complications such as retinopathy, albuminuria and coronary heart disease were associated with ED. NIH criteria diagnosed a much lower rate of ED compared with IIEF-5. Overall, structured questionnaires are useful and objective tools to detect ED, which should prompt a comprehensive risk assessment in these subjects. |
| | |
Authors:
|
L W Yu; A P Kong; P C Tong; C Tam; G T Ko; C-S Ho; W-Y So; R C Ma; C-C Chow; J C Chan |
Related Documents
:
|
19734534 - Pay for perfomance and the quality of diabetes management in individuals with and witho... 20123914 - Depressive disorder and incident diabetes mellitus: the effect of characteristics of de... 15101024 - Albuminuria as a predictor of heart failure hospitalizations in patients with type 2 di... 17919274 - Severe symptoms of gastro-oesophageal reflux disease are associated with cardiovascular... 20440254 - Diabetes and cardiovascular outcomes: finding the silver lining. 18377784 - Behavioral management of obesity. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International journal of andrology Volume: 33 ISSN: 1365-2605 ISO Abbreviation: Int. J. Androl. Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-09 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8000141 Medline TA: Int J Androl Country: England |
Other Details:
|
Languages: eng Pagination: 853-60 Citation Subset: IM |
Copyright Information:
|
© 2010 The Authors. International Journal of Andrology © 2010 European Academy of Andrology. |
Affiliation:
|
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The effects of an in utero exposure to 2,3,7,8-tetrachloro-dibenzo-p-dioxin on male reproductive fun...
Next Document: Catalase can protect spermatozoa of FSH receptor knock-out mice against oxidant-induced DNA damage i...