| Evaluation of endothelial function using finger plethysmography. | |
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MedLine Citation:
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PMID: 19552735 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The aims of this study were to establish the optimum duration of blood flow occlusion to obtain maximal response and to compare the response after lower-arm and upper-arm occlusion. METHODS: Pulse wave amplitude was analysed using a novel finger plethysmograph (EndoPat; Itamar). For measuring reactive hyperaemic index (RHI) induced by forearm cuff occlusion, 30 healthy subjects were examined at different days in a random order of four cuff occlusion times (1.5, 3, 5 and 8 min). RHI induced by 5 min upper-arm cuff occlusion was also measured in 20 subjects. RESULTS: Average RHI was lower with 1.5 and 3 min forearm occlusion compared with 8 min forearm occlusion (P = 0.002 and P = 0.024). There was no significant difference between values of 5 min and 8 min forearm occlusion and between 5 min forearm and 5 min upper-arm occlusion (P = 0.1). All subjects reported less discomfort after forearm occlusion compared with upper-arm occlusion. CONCLUSION: Maximum response was reached after 5 min of blood flow occlusion and therefore this occlusion time is recommended. The response after forearm and upper-arm occlusion did not differ significantly. Forearm occlusion might be preferred as this caused less discomfort. |
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Authors:
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A K Faizi; D W Kornmo; S Agewall |
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Publication Detail:
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Type: In Vitro; Journal Article Date: 2009-06-22 |
Journal Detail:
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Title: Clinical physiology and functional imaging Volume: 29 ISSN: 1475-097X ISO Abbreviation: - Publication Date: 2009 Sep |
Date Detail:
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Created Date: 2009-08-27 Completed Date: 2009-11-05 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101137604 Medline TA: Clin Physiol Funct Imaging Country: England |
Other Details:
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Languages: eng Pagination: 372-5 Citation Subset: IM |
Affiliation:
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Department of Medicine, Aker University Hospital and Oslo University, Oslo 0514, Norway. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Flow Velocity / physiology* Endothelium, Vascular / physiology* Female Fingers / blood supply*, physiology* Humans Hyperemia / physiopathology* Male Middle Aged Plethysmography / methods* Reproducibility of Results Sensitivity and Specificity |
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