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Evaluation of different magnetic resonance imaging techniques for the assessment of active left atrial emptying.
MedLine Citation:
PMID:  22538633     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
OBJECTIVES: There is currently no agreement on the best method of assessing active left atrial (LA) emptying. This study evaluated the relative merits of cine- and velocity encoded (VENC) magnetic resonance imaging (MRI) for the assessment of active LA emptying. METHODS: Total LA emptying volume (TLAEV) and active LA stroke volume (ALASV) were assessed in 107 consecutive patients using cine-MRI and transmitral flow measurements by VENC-MRI. The fraction of active LA emptying (ALAEF) was calculated as the ratio of ALASV to TLAEV. LA and left ventricular (LV) output were calculated by multiplying TLAEV and LV stroke volume by heart rate, respectively. RESULTS: Intra- and inter-observer variances were significantly larger for cine-MRI than for VENC-MRI measurements of ALASV (24.7 mL(2) vs. 3.7 mL(2) and 57.7 mL(2) vs. 4.2 mL(2); P < 0.0001). Biplane cine-MRI underestimated TLAEV (mean difference -57 ± 32 %; P < 0.0001) and ALASV (mean difference -24 ± 51 %; P < 0.0001) but overestimated ALAEF (mean difference 31 ± 54 %, P < 0.0001) compared with VENC-MRI. There was significantly better agreement between LV output and LA output measured by VENC-MRI compared with LA output measured by cine-MRI (mean difference 0.30 ± 1.12 L/min vs. -2.05 ± 1.44 L/min; P < 0.0001). CONCLUSION: VENC-MRI is the more appropriate method of assessing active LA emptying and its use should be favoured. KEY POINTS : • Cardiac magnetic resonance imaging (MRI) offers new possibilities in assessing atrial emptying. • Cine-MRI measurements of active LA emptying have lower reproducibility than velocity encoded MRI. • Cine-MRI overestimates the fraction of active LA emptying compared with VENC-MRI. • VENC-MRI is the more appropriate method of assessing active LA emptying.
Authors:
Kai Muellerleile; Michael Groth; Dennis Saring; Daniel Steven; Arian Sultan; Imke Drewitz; Boris Hoffmann; Jakob Lueker; Gerhard Adam; Gunnar K Lund; Stephan Willems; Thomas Rostock
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-27
Journal Detail:
Title:  European radiology     Volume:  -     ISSN:  1432-1084     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Cardiology, Electrophysiology, Center for Cardiology and Cardiovascular Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany, ka.muellerleile@uke.de.
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