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Evaluation of diagnostic criteria for Crohn's disease in Japan.
MedLine Citation:
PMID:  23546557     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
BACKGROUND: In Japan, Crohn's disease (CD) is diagnosed according to a single, well-established set of diagnostic criteria. However, no nationwide attempt has been made to determine which specific criteria within these diagnostic criteria are used to make diagnoses. METHODS: A questionnaire-based survey was conducted of patients given a definitive or suspected diagnosis of CD before January 2011 according to the Japanese Diagnostic Criteria for Crohn's Disease. The survey included 579 patients with a definitive diagnosis of CD and 59 patients with a suspected diagnosis of CD at 34 Japanese medical institutions. RESULTS: A total of 87.4 % of definitive diagnoses of CD were based on the criterion in the definite category: major finding A "longitudinal ulcer (LU)" or B "cobblestone-like appearance (CSA)". A total of 30.4 % of definitive diagnoses were based on the criterion: major finding C "non-caseating epithelioid cell granuloma (NCEG)" with minor finding a "irregularshaped and/or quasi-circular ulcers or aphthous ulcerations found extensively in the gastrointestinal tract" or b "characteristic perianal lesions". Finally, 7.1 % of definitive diagnoses were made according to the criterion: all minor findings a, b and c "characteristic gastric and/or duodenal lesions". Among suspected diagnoses of CD, 74.6 % were based on the criterion in the suspected category: one or two minor findings. CONCLUSIONS: The Japanese diagnostic criteria for Crohn's disease consist of combinations of specific morphological findings. Many of the diagnoses were based on the findings of LU or CSA.
Authors:
Takashi Hisabe; Fumihito Hirai; Toshiyuki Matsui; Mamoru Watanabe
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-4-3
Journal Detail:
Title:  Journal of gastroenterology     Volume:  -     ISSN:  1435-5922     ISO Abbreviation:  J. Gastroenterol.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-4-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9430794     Medline TA:  J Gastroenterol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Gastroenterology, Fukuoka University Chikushi Hospital, 1-1-1 Zokumyoin, Chikushino, Fukuoka, 818-8502, Japan, hisabe@cis.fukuoka-u.ac.jp.
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