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Evaluation of coronary artery in-stent patency using 64-slice computed tomography.
MedLine Citation:
PMID:  21959714     Owner:  NLM     Status:  Publisher    
BACKGROUND: Surveillance conventional coronary angiography (CCA) is recommended after stent supported percutaneous coronary intervention due to the unpredictable occurrence of in-stent restenosis (ISR). We explored the ability of 64-slice computed tomography angiography (CTA) to detect ISR after stenting of the coronary artery and analyzed the factors influencing imaging quality. MATERIALS AND METHODS: Forty-five consecutive patients (29 stents) were examined by both CCA and 64-slice CTA after percutaneous coronary intervention. We analyzed the correlation between the image quality and heart rate, diameter, position, and stent-strut thickness. Compared with the CCA, the sensitivity, specificity, positive predictive value, and negative predictive value of 64-slice CTA for the detection of ISR were calculated. Between the patent group and ISR group, different computed tomography attenuation values of the in-stent lumen and artery 5 mm proximal and distal to the stent were also analyzed. RESULTS: All stents were clearly visualized. With regard to the differences in heart rate, stent position, stent diameter, and stent-strut thickness among the different image quality groups, the P values were 0.47, 0.60, 0.04, and <0.01, respectively. Compared with CCA, the sensitivity, specificity, positive predictive value, and negative predictive value of 64-slice CTA were 100, 95.2, 88.9, and 100%, respectively. Between patent and ISR groups, the P values for the differences in CTA attenuation values of the in-stent lumen and artery 5 mm distal to the stent were 0.007 and 0.04, respectively. CONCLUSION: We found that 64-slice spiral CTA is a reliable noninvasive diagnostic method that can display the stent lumen clearly and is especially helpful for patient follow-up.
Jing Zhao; Li-Li Zheng; Youyou Yang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-28
Journal Detail:
Title:  Coronary artery disease     Volume:  -     ISSN:  1473-5830     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9011445     Medline TA:  Coron Artery Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
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