Document Detail


Evaluation of the clinical efficacy of embryo cryopreservation.
MedLine Citation:
PMID:  11155960     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To fully evaluate the advantages of a cryopreservation program a method needs to be established to express the additional patients pregnant from cryopreservation. The patient specific method considers cryopreservation as augmentation only among patients without a pregnancy from the fresh transfer, or from previously transferred frozen material from the same harvest. In an analysis of the pregnancy rate at the Jones Institute between January 1996 and December 1998 we found a fresh pregnancy rate of 40.8% in the good responders and 28.8% in poor responders. The patient specific pregnancy rate in the same cycles was 53.4% in good responders and 32.3% in poor responders. Good responders less than 35 years of age with ten or more mature eggs at retrieval had a fresh pregnancy rate of 40.2% and a patient specific pregnancy rate of 57.9%. It is exceedingly important for the physician and patient to understand and comprehend the potential in cryopreserved material.
Authors:
J A Schnorr; S J Muasher; H W Jones
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Molecular and cellular endocrinology     Volume:  169     ISSN:  0303-7207     ISO Abbreviation:  Mol. Cell. Endocrinol.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-01-11     Completed Date:  2001-04-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7500844     Medline TA:  Mol Cell Endocrinol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  85-9     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Jones Institute for Reproductive Medicine, Eastern Virginia Medical School, Norfolk, VA 23507, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Blastocyst / cytology*
Clinical Protocols
Cryopreservation / methods,  standards*
Female
Humans
Models, Biological
Pregnancy
Pregnancy Rate
Pregnancy, Multiple

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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