Document Detail

Evaluation of certain food additives and contaminants. Forty-ninth report of the Joint FAO/WHO Expert Committee on Food Additives.
MedLine Citation:
PMID:  10079756     Owner:  NLM     Status:  MEDLINE    
This report presents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of various food additives and contaminants, with a view to recommending acceptable daily intakes for humans, and to prepare specifications for the identity and purity of food additives. The first part of the report contains a general discussion of the principles governing the toxicological evaluation of food additives and contaminants, including flavouring agents, and the establishment and revision of specifications, with comments concerning limits for arsenic, lead and other heavy metals, and enzymes derived from genetically manipulated organisms. A summary follows of the Committee's evaluations of toxicological data on various specific food additives (tert-butylhydroquinone (TBHQ), microcrystalline cellulose, sucrose esters of fatty acids and sucroglycerides, alpha-acetolactate decarboxylase, maltogenic amylase, trans-anethole, hydrogenated poly-1-decene and maltitol syrup), food ingredients (short- and long-chain acyltriglycerides), flavouring agents and the contaminants aflatoxins. Annexed to the report are tables summarizing the Committee's recommendations for acceptable daily intakes of the food additives and food ingredients considered, changes in the status of specifications for these substances and specific flavouring agents, and further toxicological studies required.
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Publication Detail:
Type:  Technical Report    
Journal Detail:
Title:  World Health Organization technical report series     Volume:  884     ISSN:  0512-3054     ISO Abbreviation:  World Health Organ Tech Rep Ser     Publication Date:  1999  
Date Detail:
Created Date:  1999-03-31     Completed Date:  1999-03-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7903212     Medline TA:  World Health Organ Tech Rep Ser     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  i-viii, 1-96     Citation Subset:  IM    
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MeSH Terms
Flavoring Agents / adverse effects,  analysis
Food Additives / adverse effects,  analysis*
Food Contamination / analysis*
World Health Organization
Reg. No./Substance:
0/Flavoring Agents; 0/Food Additives

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