| Evaluation of cerebral perfusion parameters measured by perfusion CT in chronic cerebral ischemia: comparison with xenon CT. | |
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MedLine Citation:
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PMID: 11884786 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The purpose of this work was to evaluate the usefulness of perfusion CT in the evaluation of patients with chronic cerebral ischemia by comparing it with xenon CT (Xe-CT). METHOD: Cerebral blood flow (CBF) of perfusion CT (CBFper) and time to peak (TTP) were compared with the CBF of Xe-CT (CBFxe) in 18 patients. Cerebral blood volume (CBV) was compared with cerebral vascular reserve (CVR) in 10 of 18 patients who underwent pre- and postacetazolamide Xe-CT. RESULTS: CBFper and TTP demonstrated a high correlation with CBFxe in relative values by side-to-side comparisons (r = 0.743, p < 0.0001 and r = -0.760, p < 0.0001, respectively). There was a negative correlation between relative CBV and relative CVR (r = -0.637, p = 0.0025). Visually, territories with delayed TTP corresponded well to those of decreased CBFxe, but these territories tended to be larger in TTP maps. CONCLUSION: Perfusion CT is a useful tool to evaluate chronic hemodynamic disturbance and can be an alternative method for those using acetazolamide challenge. |
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Authors:
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Matakazu Furukawa; Shiro Kashiwagi; Naofumi Matsunaga; Michiyasu Suzuki; Keiko Kishimoto; Satoshi Shirao |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 26 ISSN: 0363-8715 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2002 Mar-Apr |
Date Detail:
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Created Date: 2002-03-08 Completed Date: 2002-04-09 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 272-8 Citation Subset: IM |
Affiliation:
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Department of Radiology, Yamaguchi University School of Medicine, Yamaguchi, Japan. matakazu@fg7.so-net.ne.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Brain Ischemia / pathology* Cerebral Cortex / blood supply*, pathology Chronic Disease Female Hemodynamics Humans Male Middle Aged Regional Blood Flow Tomography, X-Ray Computed / methods* Xenon / diagnostic use |
| Chemical | |
Reg. No./Substance:
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7440-63-3/Xenon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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