Document Detail


Evaluation of cell impedance using a μ-channel.
MedLine Citation:
PMID:  23367179     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We propose a novel approach for evaluating both the stiffness and internal viscosity of a cell by using a μ-channel. The key idea comes from the fact that cell behavior in the channel can be separated into two phases; one is in the entrance area where the cell heavily deforms within a short distance, and the other is in the remaining area where the cell keeps almost constant shape. By focusing on the cell behavior in the first area, we can evaluate the internal viscosity of a cell. By focusing on the cell behavior in the second area, we can evaluate the stiffness. We conducted experiments with two different initial velocities of red blood cells, and discussed the results from the viewpoint of applicability.
Authors:
Chia-Hung Dylan Tsai; Makoto Kaneko; Fumihito Arai
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2012     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2012  
Date Detail:
Created Date:  2013-01-31     Completed Date:  2013-07-24     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5518-21     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Electric Impedance*
Erythrocytes / cytology*
Evaluation Studies as Topic
Humans
Viscosity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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