| Evaluation of cardiac performance by abdominal fetal ECG in twin-to-twin transfusion syndrome. | |
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MedLine Citation:
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PMID: 22886606 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate fetal cardiac performance by abdominal fetal electrocardiography (ECG) in monochorionic diamniotic pregnancies with twin-to-twin transfusion syndrome (TTTS-MCDA). METHODS: Abdominal fetal ECG was attempted in 16 singleton, 21 non-TTTS-MCDA, and 14 TTTS-MCDA pregnancies at 16-27 weeks' gestation. Standard ECG parameters were compared across study groups and evaluated for their correlation with Doppler ultrasound indices. RESULTS: Clear P-QRST complexes were recognized in all cases. In the TTTS-MCDA pregnancies, the QT interval and QTc were significantly longer than in both singletons and the non-TTTS-MCDA pregnancies (p = 0.002 and p = 0.0002, respectively), whereas in the recipient fetus, both the PR interval and PR/RR were significantly longer when compared with all other study groups (p = 0.019 and p = 0.012, respectively). Further comparison with Doppler ultrasound indices yielded significant reciprocal correlations between ductus venosus pulsatility index and the QT interval (r = 0.552, p = 0.041) and between umbilical artery pulsatility index and PR/RR (r = 0.654, p = 0.011) both demonstrated in recipient fetuses alone. CONCLUSIONS: Abdominal fetal ECG is feasible in second-trimester twin pregnancies. In TTTS, there is evidence of a higher risk of cardiac dysfunction in the recipient twin. © 2012 John Wiley & Sons, Ltd. |
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Authors:
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Clarissa Velayo; Jesus Rodriguez Calvo; Naoaki Sato; Yoshitaka Kimura; Nobuo Yaegashi; Kypros Nicolaides |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-7 |
Journal Detail:
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Title: Prenatal diagnosis Volume: - ISSN: 1097-0223 ISO Abbreviation: Prenat. Diagn. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8106540 Medline TA: Prenat Diagn Country: - |
Other Details:
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Languages: ENG Pagination: 1-7 Citation Subset: - |
Copyright Information:
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© 2012 John Wiley & Sons, Ltd. |
Affiliation:
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Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, Denmark Hill, London, UK; Department of Obstetrics & Gynecology, Tohoku University Graduate School of Medicine, Sendai, Miyagi, Japan. chinkeyvelayo@med.tohoku.ac.jp. |
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