| Evaluation of blood flow signal in small hepatic nodules by color Doppler ultrasonography. | |
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MedLine Citation:
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PMID: 8895674 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Small hepatic nodular lesions are frequently detected by ultrasonography in patients with liver cirrhosis during follow-up. However, hepatocellular carcinomas (HCCs) and non-HCC nodules are difficult to differentiate by ultrasonography because they have a similar appearance. We used color Doppler ultrasonography (CDU) to examine 29 HCCs and 26 non-HCC nodules less than 2 cm in diameter to determine whether CDU can be used to differentiate small hepatic nodules. There were no significant differences between the examined HCCs and non-HCC nodules with regard to ultrasonographic appearance, i.e., hypoechoicity or hyperechoicity. Blood flow signals were detected in a significantly higher percentage of HCCs (13 of 29, 44.8%) than in non-HCC nodules (2 of 26, 7.7%; P<0.005), although the sensitivity was low. Therefore, we classified nodules as hypoechoic or hyperechoic by B-mode ultrasonography and examined their blood flow signals. Among nodules that were hypoechoic, signals were detected in a significantly higher percentage of HCCs (12 of 18, 66.7%) than in non-HCC nodules (2 of 13, 15.4%; P<0.005). In contrast, among hyperechoic nodules, signals were detected in only 1 of 11 (9.1%) HCCs and in 0 of 13 non-HCC nodules. Our results suggest that examination of blood flow by CDU is useful for differentiating small hepatic nodules, especially hypoechoic nodules. |
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Authors:
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J Furuse; M Iwasaki; M Yoshino; M Konishi; N Kawano; T Kinoshita; M Ryu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese journal of clinical oncology Volume: 26 ISSN: 0368-2811 ISO Abbreviation: Jpn. J. Clin. Oncol. Publication Date: 1996 Oct |
Date Detail:
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Created Date: 1996-12-17 Completed Date: 1996-12-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0313225 Medline TA: Jpn J Clin Oncol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 335-40 Citation Subset: IM |
Affiliation:
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Department of Gastrointestinal Medicine, National Cancer Center Hospital East, Kashiwa, Chiba. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Blood Flow Velocity Carcinoma, Hepatocellular / blood supply*, ultrasonography* Diagnosis, Differential Evaluation Studies as Topic Female Humans Liver Neoplasms / blood supply*, ultrasonography* Male Middle Aged Ultrasonography, Doppler, Color* |
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