| Evaluation of association between exercise-induced bronchoconstriction and childhood asthma control test questionnaire scores in children. | |
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MedLine Citation:
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PMID: 22058076 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: Asthma control represents a major challenge in the management of asthmatic children; however, correct perception of control is poor. The aim of the study was to evaluate the association between subjective answers given to the Childhood Asthma Control Test (C-ACT) and objective evaluation of exercise-induced bronchonstriction (EIB) by standardized treadmill exercise challenge. METHODS: EIB was evaluated by standardized treadmill exercise challenge and related to C-ACT scores in 92 asthmatic children. RESULTS: Of the 92 studied children only six children had a concordance between a positive challenge test (ΔFEV1 ≥ 13%) and a positive response to the exercise-related issue of the C-ACT questionnaire (C-ACT total score ≤ 19). There was no significant association between the degree of EIB and the scores relative to the single question on exercise-related problems while a significant association was found when considering the whole questionnaire with C-ACT total score > 19 (r = -0.40, P < 0.001). The two single questions showing a significant association were those focusing on nocturnal asthma. The areas under the ROC curve (AUC) for the sum of the scores of these questions in relationship to a positive response to the exercise test was 0.74. The AUC of the C-ACT total score was 0.76 and 0.55 for the specific question on EIB related problems. CONCLUSION: The discrimination power of the C-ACT total score in relationship to EIB was moderately good, and C-ACT questionnaire was capable of correctly predicting the absence of EIB in children reporting a global score > 19. However, direct questions on EIB are associated with a high number of false positive and negative responses; better associations are found questioning on the presence on nocturnal symptoms. Pediatr Pulmonol. © 2011 Wiley Periodicals, Inc. |
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Authors:
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Iolanda Chinellato; Michele Piazza; Marco Sandri; Fabio Cardinale; Diego G Peroni; Attilio L Boner; Giorgio L Piacentini |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-11-4 |
Journal Detail:
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Title: Pediatric pulmonology Volume: - ISSN: 1099-0496 ISO Abbreviation: - Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-11-7 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8510590 Medline TA: Pediatr Pulmonol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Wiley Periodicals, Inc. |
Affiliation:
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Department of Paediatrics, University of Verona, Policlinico GB Rossi, Piazzale L. Scuro 10, 37134 Verona, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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