| Evaluation of arterial blood flow in esophageal varices via endoscopic color Doppler ultrasonography with a galactose-based contrast agent. | |
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MedLine Citation:
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PMID: 15692791 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: We examined the usefulness of endoscopic color Doppler ultrasonography, using Levovist in evaluating the arterial blood flow, in patients with esophageal varices. METHODS: The study involved 110 patients with esophageal varices who were examined using endoscopic color Doppler ultrasonography (ECDUS). We compared vessel images detected by pre-contrast ECDUS with those detected by enhanced ECDUS. We evaluated the detection rate of the pulsatile wave, and measured systolic velocity and end-diastolic velocity. We calculated the resistance index (RI), which demonstrates the resistance of peripheral vessels in arterial flow. RESULTS: Color flow images of the pulsatile wave were obtained by pre-contrast ECDUS in 3 (2.7%) of the 110 patients. Color flow images of the pulsatile waves were obtained in 40 (36.4%) of the 110 patients by enhanced ECDUS using Levovist. That is, by using Levovist, a pulsatile wave could be delineated in 37 patients in whom pulsatile waves were previously undiagnosed via pre-contrast ECDUS. Color flow images of the pulsatile waves were detected in 37 (37.7%) of the 98 F2 varices and in 3 (25.0%) of the 12 F3 varices. Color flow images of the pulsatile wave were detected in 35 (40.2%) of the 87 red color (RC)(+) varices, and in 5 (21.7%) of the 23 RC(++) or RC (+++) varices. Next, we calculated the RI of the pulsatile wave, obtained by enhanced ECDUS using Levovist, in 40 patients. The RI ranged from 0.49 to 0.83 (mean, 0.67 +/- 0.09); there were nine patients with RIs of less than 0.60, and all 9 of these patients had both F2 and RC(+) type varices (100%). CONCLUSIONS: Levovist contrast in ECDUS examinations suggests that arterial flow is involved in the formation of esophageal varices. |
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Authors:
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Takahiro Sato; Katsu Yamazaki; Jouji Toyota; Yoshiyasu Karino; Takumi Ohmura; Jun Akaike; Yasuaki Kuwata; Toshihiro Suga |
Publication Detail:
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Type: Case Reports; Comparative Study; Evaluation Studies; Journal Article |
Journal Detail:
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Title: Journal of gastroenterology Volume: 40 ISSN: 0944-1174 ISO Abbreviation: J. Gastroenterol. Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-04 Completed Date: 2005-12-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9430794 Medline TA: J Gastroenterol Country: Japan |
Other Details:
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Languages: eng Pagination: 64-9 Citation Subset: IM |
Affiliation:
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Department of Gastroenterology, Sapporo Kosei General Hospital, Kita 3 Higashi 8, Chuo-ku, Sapporo 060-0033, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Flow Velocity / physiology Blood Pressure / physiology Collateral Circulation / physiology Contrast Media / administration & dosage* Diastole / physiology Endosonography* Esophageal and Gastric Varices / physiopathology*, ultrasonography* Esophagus / blood supply, ultrasonography Female Galactose / administration & dosage*, diagnostic use* Humans Japan Liver Cirrhosis / physiopathology, ultrasonography Male Middle Aged Pulsatile Flow / physiology Regional Blood Flow / physiology Systole / physiology Ultrasonography, Doppler, Color* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 26566-61-0/Galactose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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