| Evaluation of the antiproliferative effect of infusions and essential oil of Aloysia gratissima. | |
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MedLine Citation:
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PMID: 20334120 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Aloysia gratissima is used in Brazilian folk medicine for the treatment of digestive and respiratory diseases. The infusions (6 and 24 g L-1) and essential oils (0.25%, on ethanol) were prepared and we used groups of five Allium cepa bulbs for each treatment. A total of 2500 cells per treatment were analyzed and the mitotic indexes were calculated. The antiproliferative effect of infusions and essential oils of Aloysia gratissima on the Allium cepa (onion) cell cycle was evaluated using the leaves of studied specimens. The infusions presented a significant decrease in the mitotic index (4.55% at 6 g L-1 and 2.04% at 24 g L-1) compared to the control-water (6.83%), as well as for the essential oil (2.58%), in comparison to the control-ethanol (3.65%). This investigation showed that the infusions and essential oil of Aloysia gratissima present important antiproliferative effects on the Allium cepa cell cycle. |
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Authors:
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C A L Hister; H D Laughinghouse; C B Da Silva; T S Do C Dorow; S B Tedesco |
Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: Pakistan journal of biological sciences: PJBS Volume: 12 ISSN: 1028-8880 ISO Abbreviation: Pak. J. Biol. Sci. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-03-25 Completed Date: 2010-04-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101247723 Medline TA: Pak J Biol Sci Country: Pakistan |
Other Details:
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Languages: eng Pagination: 1581-4 Citation Subset: IM |
Affiliation:
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Curso de Ci?ncias Biol?gicas, Universidade Federal de Santa Maria, Av. Roraima, 1000, Santa Maria, RS, Brasil. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antineoplastic Agents
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pharmacology* Brazil Cell Cycle / drug effects Humans Medicine, Traditional Oils, Volatile / pharmacology* Onions / cytology, drug effects, physiology Verbenaceae / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents; 0/Oils, Volatile |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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