Document Detail


Evaluation of the antioxidant capacity of limonin, nomilin, and limonin glucoside.
MedLine Citation:
PMID:  16719503     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The antioxidant capacity (AOC) of three representative citrus limonoids, limonin, nomilin, and limonin glucoside, was examined by the oxygen radical absorbance capacity (ORAC), Trolox equivalent antioxidant capacity (TEAC), beta-carotene-linoleic acid bleaching, and 1,1-diphenyl-2-picryl hydrazyl (DPPH) radical scavenging assays. Pure compounds and proper negative (cinnamic acid) and positive (2,6-di-tert-butyl-4-methylphenol (BHT) and ascorbic acid) controls were used to remove any ambiguity in interpreting results. In all cases, limonin and nomilin gave results equivalent to those of cinnamic acid, indicating that they do not possess any inherent AOC and should not be considered antioxidants. Similar results were observed for limonin glucoside, with the exception of an anomalous result obtained from the beta-carotene-linoleic acid bleaching assay. Limonin glucoside was deemed not to be an antioxidant on the basis of the three unequivocal assays.
Authors:
Andrew P Breksa; Gary D Manners
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  54     ISSN:  0021-8561     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-24     Completed Date:  2006-06-29     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3827-31     Citation Subset:  IM    
Affiliation:
Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 800 Buchanan Street, Albany, California 94710, USA. apb3@pw.usda.gov
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MeSH Terms
Descriptor/Qualifier:
Antioxidants / pharmacology*
Benzoxepins / pharmacology*
Biphenyl Compounds
Chromans
Glucosides / pharmacology*
Limonins / pharmacology*
Linoleic Acid / chemistry
Picrates
Reactive Oxygen Species / chemistry
beta Carotene / chemistry
Chemical
Reg. No./Substance:
0/Antioxidants; 0/Benzoxepins; 0/Biphenyl Compounds; 0/Chromans; 0/Glucosides; 0/Limonins; 0/Picrates; 0/Reactive Oxygen Species; 1063-77-0/nomilin; 1180-71-8/limonin; 1898-66-4/2,2-diphenyl-1-picrylhydrazyl; 2197-37-7/Linoleic Acid; 56305-04-5/6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; 7235-40-7/beta Carotene

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